Protein Alignment CG6204 and MOV10L1

DIOPT Version :9

• Sequence 1: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Sequence 2: XP_011528998.1
• Gene: MOV10L1 / 54456
• HGNCID: 7201
• Length: 1256
• Species: Homo sapiens
• Alignment Length: 887
• Identity: 183/887 - (20%)
• Similarity: 299/887 - (33%)
• Gaps: 318/887 - (35%)

  Fly   124 LSAFSRQTALLDKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHGLLSHQGYELVELYKKL 188
            |.:|..|..:.|:::..::.|..:.......|.:|:.|.:    ..|...|    ..|.|:|.::
Human   491 LPSFLPQYPIPDRLRKCVEQKIDILTFQPLLAELLNMSNY----KEKFSTL----LWLEEIYAEM 547

  Fly   189 APSFKSDMIDGLEAFTGNFSHNVKGLIYPTLETLLGKDATKAPNEEEDEGLVSDKVVKYVNALRN 253
            ...                .:|:.|:|......||   ..:.|      ||...:...|......
Human   548 ELK----------------EYNMSGIILRRNGDLL---VLEVP------GLAEGRPSLYAGDKLI 587

  Fly   254 LLREDFLAPLVEFVQQLRSGTDVDELKQQGLLWSDVHLTLNPQFANAQRHSLVFLKVQFTKESKN 318
            |..:::....:|::..:   |::.|        .||.|.:||:|  .|.::...:.|:||...
Human   588 LKTQEYNGHAIEYISYV---TEIHE--------EDVTLKINPEF--EQAYNFEPMDVEFTYNR-- 637

  Fly   319 AYKTWLNSIKSGTLLCLTTS----LAFDDLILASVGYTEPEKLKEDCLSVQIVKQYNIG------ 373
                             |||    .|.:.:|...|....||::  ...|.|:...:|..
Human   638 -----------------TTSRRCHFALEHVIHLGVKVLFPEEI--ILQSPQVTGNWNHAQDTKSS 683

  Fly   374 ----NAYNRPLIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGRYIVDGQMEIPPP--AYMKPGV-- 430
                :..||..:..||.         |      .||:    |.:.|..:.:..|  |.|...|
Human   684 GQSTSKKNRKTMTDQAE---------H------GTEE----RRVGDKDLPVLAPFTAEMSDWVDE 729

  Fly   431 -------KLSFNMKPFTLDKLPEDLHLNESQKTAFKEAL---CREFS-IIQGPPGTGKTHLSVQL 484
                   |:.| ..|.          |||:||.|.|..|   ||... |:.||||||||   |.:
Human   730 IQTPKARKMEF-FNPV----------LNENQKLAVKRILSGDCRPLPYILFGPPGTGKT---VTI 780

  Fly   485 VNSLIQNAKALGTGPIIVLTYTNNSLDKFLVKISRYTQEILRFGNQSRDPQISKFNLSTTIKPEL 549
            :.:::|...||....|:|...:|::.|  ||.:..:..::|:
Human   781 IEAVLQVHFALPDSRILVCAPSNSAAD--LVCLRLHESKVLQ----------------------- 820

  Fly   550 VPPRLKRIWWLVNCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEKLNQVAERIETLRMVFQFFL 614
             |..:.|:  ...|.::|...:....|.. || |:.::            |.|...:
Human   821 -PATMVRV--NATCRFEEIVIDAVKPYCR-DG-EDIWK------------ASRFRII-------- 860

  Fly   615 AREKDLLAMTTTCAARHNFL---FRLLQSKCVLFEEAAEIQEAHIVACLTP------HTEHVILV 670
                     .|||::...|.   .|:.....|..:||.:..|..   ||.|      .:..::|.
Human   861 ---------ITTCSSSGLFYQIGVRVGHFTHVFVDEAGQASEPE---CLIPLGLMSDISGQIVLA 913

  Fly   671 GDHKQLQPFSGSRKVP----QISLFERLIVAGLPFSRLNLQ---YRMRSCISELLVPSIYDELLC 728
            ||..||.|...||...    .:|..|||:      ||...|   ....:|       ..::.||.
Human   914 GDPMQLGPVIKSRLAMAYGLNVSFLERLM------SRPAYQRDENAFGAC-------GAHNPLLV 965

  Fly   729 SESVKEY---EDIRLMSKNLYFVQHNQPEHCMSDMSIGNLY------------------------ 766
            ::.||.|   |.:.::...|::  |.:.|.|.....:.:|.
Human   966 TKLVKNYRSHEALLMLPSRLFY--HRELEVCADPTVVTSLLGWEKLPKKGFPLIFHGVRGSEARE 1028

  Fly   767 ----------EAGVLAKLTEFLIQ--KAQYKHSDIVILSPY------------------------ 795
                      ||..:.:....|..  .:|...|||.:::||
Human  1029 GKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPYRKQWLWSSGGDTGASHAEHQVSFM 1093

  Fly   796 --------NGQIECIKNALPQNYRSTVQ---------------VASVDSFQGLEANIVLLSLVRS 837
                    :.|.|..||  |||....|:               |.||:.|||.|..::::|.|||
Human  1094 KHVSLWCSHHQAELGKN--PQNTEEKVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRS 1156

  Fly   838 NISGR-------IGFLRQANRVCVALSRARWALYIVGNVTIL 872
            | ..|       :|||..:.|..||::|.:..|.::||..:|
Human  1157 N-EDRFEDDRYFLGFLSNSKRFNVAITRPKALLIVLGNPHVL 1197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	57/242 (24%)
		AAA_19	467..>513	CDD:289986	17/46 (37%)
		UvrD_C_2	688..869	CDD:304668	58/276 (21%)
MOV10L1	XP_011528998.1	DNA2	426..1217	CDD:224037	183/887 (21%)
		P-loop_NTPase	744..>922	CDD:304359	57/252 (23%)
		AAA_12	933..1194	CDD:289832	58/278 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810