Protein Alignment CG6204 and upf1

DIOPT Version :9

• Sequence 1: NP_651229.2
• Gene: CG6204 / 42877
• FlyBaseID: FBgn0039165
• Length: 903
• Species: Drosophila melanogaster
• Sequence 2: NP_998639.1
• Gene: upf1 / 406783
• ZFINID: ZDB-GENE-040426-2836
• Length: 1100
• Species: Danio rerio
• Alignment Length: 745
• Identity: 188/745 - (25%)
• Similarity: 309/745 - (41%)
• Gaps: 165/745 - (22%)

  Fly   229 KAPNEEEDEGLVSDKV-VKYVNALRNLLREDFLAPLVEFVQQLRSGTDVDELKQQGLLWSDVHLT 292
            |.|:|:|.  |.:.:: .:.:|.|..|.:|:..|.|             ::|::.|:.....|:.
Zfish   223 KIPSEQEQ--LRARQITAQQINKLEELWKENPTATL-------------EDLEKPGVDEEPQHVL 272

  Fly   293 LNPQFANAQRHSLVF-----LKVQFTKESK------NAYKTW---LNS----------------- 326
            |  ::.:|.::..:|     |:..:.|:.|      |....|   ||.
Zfish   273 L--RYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSGDMR 335

  Fly   327 IKSGTLLCLTTSLAFDDL--ILASVGYT--EPEKLKEDCLSVQIVKQYNIGNAYNRPLIMFQAPV 387
            :..|..:||...   .|:  :...:|:.  .|:...::   :.|..:.:.|.....| ..||...
Zfish   336 LMQGDEICLRYK---GDMAPLWKGIGHVIKVPDNYGDE---IAIELRSSAGAPVEVP-HNFQVDF 393

  Fly   388 FFE--PYLRVHNYLSTCSTEKFPMGRYI-----------VDGQMEIPPPAYMKPGVKLSFNMKPF 439
            .::  .:.|:.:.|.|.:.::..:..||           |..:.::|               |.|
Zfish   394 VWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVIIKCQLP---------------KRF 443

  Fly   440 TLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTGPIIVLT 504
            |...||:   ||.||..|.|..|.|..|:||||||||||..|..:|..|.:.    |.||::|..
Zfish   444 TAQGLPD---LNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLARQ----GNGPVLVCA 501

  Fly   505 YTNNSLDKFLVKISRYTQEILRFGNQSR---DPQISKFNLSTTIK-----PELVPPRLKRIWWLV 561
            .:|.::|:...||.:...:::|...:||   |..:|...|...|:     |||
Zfish   502 PSNIAVDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPEL------------ 554

  Fly   562 NCEYKEKFRNLQGLYANFDGSEESYQDTLAAQEKLNQVAERIETLRMVFQFFLAREKDLLAMTTT 626
                 :|.:.|:........|:|                :|...|:...:..|....|::.  .|
Zfish   555 -----QKLQQLKDETGELSSSDE----------------KRYRALKRTAERELLMNADVIC--CT 596

  Fly   627 CAARHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTP---HTEHVILVGDHKQLQPFSGSRKVPQI 688
            |....:.....:|.:.:|.:|:.:..|..   |:.|   ..:.:||||||.||.|....:|..:.
Zfish   597 CVGAGDPRLAKMQFRSILIDESTQATEPE---CMVPVVLGAKQLILVGDHCQLGPVVMCKKAAKA 658

  Fly   689 ----SLFERLIVAGLPFSRLNLQYRMRSCISELLVPSIYDELL-----CSESVKEYEDIRLMSKN 744
                ||||||:|.|:...||.:||||...:|.......|:..|     .::.:|:..|.:....:
Zfish   659 GLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAADRLKKGFDFQWPQPD 723

  Fly   745 ---LYFVQHNQPEHCMSDMSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECI---- 802
               .::|...|.|...|..|..|..||..:.|:|..|: ||..|...|.|::||.||...:
Zfish   724 KPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTRLL-KAGAKPDQIGIITPYEGQRSYLVQYM 787

  Fly   803 --KNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYI 865
              ..:|.......|::||||:|||.|.:.::||.||:|....||||....|:.|||:|||:.:.|
Zfish   788 QFSGSLHTKLYQEVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVII 852

  Fly   866 VGNVTILKDTFPKIWNPIVKRLKENNAIGE 895
            |||...|..  ..:||.::...||...:.|
Zfish   853 VGNPKALSK--QPLWNHLLNYYKEQKVLVE 880

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	64/240 (27%)
		AAA_19	467..>513	CDD:289986	20/45 (44%)
		UvrD_C_2	688..869	CDD:304668	68/198 (34%)
upf1	NP_998639.1	UPF1_Zn_bind	100..251	CDD:286500	8/29 (28%)
		DNA2	124..889	CDD:224037	188/745 (25%)
		AAA_19	457..>514	CDD:289986	24/60 (40%)
		AAA_12	660..857	CDD:289832	69/197 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810