DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6204 and Znfx1

DIOPT Version :10

Sequence 1:NP_651229.2 Gene:CG6204 / 42877 FlyBaseID:FBgn0039165 Length:903 Species:Drosophila melanogaster
Sequence 2:NP_001376200.1 Gene:Znfx1 / 296384 RGDID:1306344 Length:1907 Species:Rattus norvegicus


Alignment Length:1149 Identity:287/1149 - (24%)
Similarity:463/1149 - (40%) Gaps:348/1149 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 LLQGLEKSLKS----------LELQKNEEYIECPPSERKCPPSEVGEYVMQHTRFSLTELTNALK 70
            :.|.|.|:..|          |.:..|.:::      |.|.|:    ||:......:.::.|  :
  Rat   180 ICQVLRKACSSRIDRQSILHVLGILNNSKFL------RVCLPA----YVVGMITEPVPDIRN--Q 232

  Fly    71 MPA-IDMFLYFLSDKRDLFENQVLATDNVKRVGLFVDVL-WSLCELELGGFDEVFLSAFSRQTAL 133
            .|. |...:..|.|...:|     ...:|:...:.:.:| .||..|...|.|      ...:|. 
  Rat   233 YPEHISNIISLLQDLVSVF-----PASSVQETSMLISLLPTSLNALRASGVD------IEEETE- 285

  Fly   134 LDKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHGLLSHQGYELVELYKKLAPSFKSDMID 198
                |||.:.:|           |:.|    |....:.|.|....|.||:          :::..
  Rat   286 ----KNLEKVQA-----------IIKH----LQEKRREGTLRVDTYTLVQ----------AEVEG 321

  Fly   199 GLEAFTGNFSHNVKGLIYPTL-ETLLGKDATKAPNEEEDEGLVSDK---VVKYVNALRNLLREDF 259
            .:|::...       .||||. |..|.:.....||      ::|.|   ...|::....||||||
  Rat   322 EVESYRAM-------PIYPTYNEVHLDERPFLRPN------IISGKYESTAVYLDTHFRLLREDF 373

  Fly   260 LAPLVEFVQQLRSGTDVDELKQQGLLWSDVHLTLNPQFANAQ-RHSLVFLKVQF-TKESKNAYKT 322
            :.||.|.:.:|....:...|:::  .:.|:.:..:.:..... ..|.:..|||| ||..|  :..
  Rat   374 VRPLREGILKLLQSFEDQCLRKR--KFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLK--FVR 434

  Fly   323 WLNS--IKSGTLLCLTTSLAFDDLILASVGYTEPEKLKEDCL-------SVQIVKQYNIGNAYNR 378
            |.||  :..|:|:|::.. .|:..:.|:|...|.|.|.:..:       |.|::......:::  
  Rat   435 WQNSKRLLYGSLVCMSKD-NFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSF-- 496

  Fly   379 PLIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGRYIVDGQMEIPPPAYMKPGVKLSF--------- 434
              :|.:...:||.|..|...|.....|..|..|.||:....:..|.|:..|.|..|         
  Rat   497 --LMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECDSYVREPRYLLMGGKYDFTPLIENPSA 559

  Fly   435 ----------------NMKPFTLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQ 483
                            |:..|:...:.|.|:|::||..|.:.||.||.:|||||||||||::.::
  Rat   560 IRKSLRGAEVLRRSKINVLDFSQWPVKEALNLDDSQMKALQFALTRELAIIQGPPGTGKTYVGLK 624

  Fly   484 LVNSLIQNAKALGTG----PIIVLTYTNNSLDKFLVKI-SRYTQEILRFGNQSRDPQISKFNL-S 542
            :|.:|:.|.......    ||:|:.|||::||:||..| ......|:|.|.:|....:.:|.| .
  Rat   625 IVQALLTNKSVWQISAQKFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRE 689

  Fly   543 TTIKPEL---VPPRLKRIWWLVNCEYKEKFRNLQ------------------------------- 573
            ...|.|.   :|..|:|.:..:..|.||..:.||                               
  Rat   690 LRNKREFRRTLPMHLRRAYMNIVTEMKESEQKLQVGAQTLECTMHGVLREQHLEKYIAPQHWESL 754

  Fly   574 -------------------------GL----------------YANFDGSEESY----------- 586
                                     ||                .|..:|.||..           
  Rat   755 MNGPVQDADWLCVQPSKHSMIVEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIE 819

  Fly   587 --------------------------------------------QDT--------LAAQE----- 594
                                                        ||.        .||:|     
  Rat   820 EEADLIQADRVIEEEEVVRPRRRKKEENGADQELAKMLLAMRLDQDVPGTTAGPEQAAEEWETQR 884

  Fly   595 ---------------KLNQV--------------------------------------------- 599
                           |||.:                                             
  Rat   885 SQKKKMKRRVKVELRKLNTITEAEASAIQDVWQLDLSSRWQLYRLWLQMYQSDTRRKILSYERQY 949

  Fly   600 ---AERIETLRMVFQFFLAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEAHIVACLT 661
               |||:..||:.....:.::..::.||||.||::..:.:.::.:.|:.|||||:.|||.:|.|:
  Rat   950 RTWAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLS 1014

  Fly   662 PHTEHVILVGDHKQLQPFSGSRKVP-----QISLFERLIVAGLPFSRLNLQYRMRSCISELLVPS 721
            ...:|:||:|||:||:|.:....:.     ::||||||:...:||.|||.|:|||..|:.||.|.
  Rat  1015 KACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNVPFVRLNYQHRMRPEIARLLTPH 1079

  Fly   722 IYDELLCSESVKEYEDIRLMSKNLYFVQHNQPEHCMSD-MSIGNLYEAGVLAKLTEFLIQKAQYK 785
            ||.:|....||.:||.|:.:|.||:||:||.||..:.: .|..|.:||..:.:|.::|:.: :|.
  Rat  1080 IYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYL 1143

  Fly   786 HSDIVILSPYNGQIECIKNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQAN 850
            .|.|.||:.|.||:.|::..:|....:.::|..||.:||.|.:::||||||||..|::|||:..|
  Rat  1144 PSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDVILLSLVRSNQEGKVGFLQIPN 1208

  Fly   851 RVCVALSRARWALYIVGNVTILKDTFPKIWNPIVKRLKENNAIG 894
            |:|||||||:..:|.:||:.:|...  .:|:.|:..|:||:.||
  Rat  1209 RICVALSRAKKGMYCIGNMQMLAKV--PLWSRIIHTLRENHQIG 1250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6204NP_651229.2 EEXXEc_NFX1 449..708 CDD:350694 105/475 (22%)
SF1_C_Upf1 710..888 CDD:350195 72/178 (40%)
Znfx1NP_001376200.1 DNA2 483..1246 CDD:440729 202/769 (26%)
EEXXEc_NFX1 <971..1066 CDD:350694 37/94 (39%)
SF1_C_Upf1 1068..1244 CDD:350195 72/178 (40%)
NF-X1-zinc-finger 1365..1411 CDD:100116
NF-X1-zinc-finger 1453..1497 CDD:100116
LELP1 1476..1553 CDD:464464
PRK03918 <1597..>1755 CDD:235175
DUF6539 1833..1877 CDD:466324
Blue background indicates that the domain is not in the aligned region.

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