DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6204 and F53E10.5

DIOPT Version :9

Sequence 1:	NP_651229.2	Gene:	CG6204 / 42877	FlyBaseID:	FBgn0039165	Length:	903	Species:	Drosophila melanogaster
Sequence 2:	NP_503712.2	Gene:	F53E10.5 / 186167	WormBaseID:	WBGene00018761	Length:	460	Species:	Caenorhabditis elegans

Alignment Length:	377	Identity:	76/377 - (20%)
Similarity:	132/377 - (35%)	Gaps:	106/377 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SSDDDWFDQ-DENKLLQGLEKS-LKSLELQKNEEYIECPPSERKCPPSEVGEYVMQHTRFSLTEL 65
            :|..:|.:| |:..|.:..|:: |....|....:|.   ||.|:...:..|.|.........|..
Worm    95 TSRGNWNEQLDDLFLAEYREQTHLSQHRLPDIADYF---PSSREPNSTGNGHYNDDGNARQSTPQ 156

  Fly    66 TNALKMPAIDMFLYFLSDKRDLFENQVLATDNVKRVGLFVDVLWSLCELELGGFDE--VFLSAFS 128
            .|..::..|.:.||...:               .::|.|        |:.|..|.|  |.:...:
Worm   157 FNQAEIAPISVPLYHAHN---------------SQIGHF--------EMTLPVFQEHQVMIHCQA 198

  Fly   129 RQ----------TALL--------DKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHGL-- 173
            .|          |.||        |:||...|...|..:...::||..|..:...|::....:
Worm   199 NQPFKPRHRIKKTELLMLTEQEKKDRIKKQNQRNTANYELKKKTALEKSRYELPRLQSRLDEVKR 263

  Fly   174 ----LSHQGYELVELYKKLAPSFKSDMIDG-LEAFTGNF---------------SHNVKGL--IY 216
                :.:|   :.::|:.::.|:.:..:.| .|.|.|..               ..|::.|  :.
Worm   264 RTREIENQ---VSDVYRIISQSYNTSYLYGSFEDFIGTLQQEKARRINEITEENKENIEHLQKMS 325

  Fly   217 PTLETLLGK-DATKAPNEEEDEGLV---------------SDKVVKYVNALRNLLREDFLAPLVE 265
            .|.|.||.. ...||||:|:.:..:               ..|.:.|...|..:..|.|.| :.|
Worm   326 TTAEKLLNDLKNNKAPNDEKGKMTIKGTKGSRKTRAKQSAESKTLAYKIRLGEVEIEKFQA-ISE 389

  Fly   266 FVQQ---------LRSGTDVDELKQQGLLW---SDVHLTLNP--QFANAQRH 303
            .::|         |.:|...:...::.|..   |||...|:|  ....|:||
Worm   390 TLEQIAKNVAQFVLENGIPANYFYERPLHTEDRSDVSHALDPTCSLLPARRH 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831
		AAA_19	467..>513	CDD:289986
		UvrD_C_2	688..869	CDD:304668
F53E10.5	NP_503712.2	CwlO1	217..374	CDD:226400	29/159 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900