DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6204 and R03D7.2

DIOPT Version :9

Sequence 1:	NP_651229.2	Gene:	CG6204 / 42877	FlyBaseID:	FBgn0039165	Length:	903	Species:	Drosophila melanogaster
Sequence 2:	NP_001364577.1	Gene:	R03D7.2 / 174682	WormBaseID:	WBGene00010989	Length:	390	Species:	Caenorhabditis elegans

Alignment Length:	310	Identity:	79/310 - (25%)
Similarity:	136/310 - (43%)	Gaps:	34/310 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   582 SEESYQDTLAAQEKL--NQVAERIETLRMVFQFFLAREKDLLAMTTTCAARHNFL---FRLLQSK 641
            :|:....||:|..||  ..:.:.:..||:    |:......|.:.|..|.:..|.   |..::.:
Worm     3 NEDLINPTLSAAVKLPYTSIPKEMTILRV----FMNIHDPQLVIGTAAAIKLAFSQAPFLEIKDR 63

  Fly   642 --CVLFEEAAEIQEAHI--VACLTPHTEHVILVGDHKQLQPFSGS---RKVPQISLFERLIVA-- 697
              ....:||:::....:  :|.:.|.: .:|||||..||.|:...   .::.:.::.|.|.:|
Worm    64 FDITFIDEASQLALYVLGSLATMLPKS-RMILVGDMHQLPPYMEEALPAELKRAAIGEPLTLAVK 127

  Fly   698 --GLPFSRLNLQYRMRSCISELLVPSIYDELLCSE-----SVKEYEDIRLMSKN-LYFVQHNQPE 754
              ..|...|...:|....|:|:|....|...|.|.     .:...:.:.|.|:: :.||.:..|:
Worm   128 GRRWPSMHLTRVHRCPKMITEVLGDLFYGNTLTSSKPGVTDIPVLKAMGLPSRHPMVFVNYTSPQ 192

  Fly   755 HCMSDMSIGNLYEAGVLAKLTEFLIQKAQYKHSDI--VILSPYNGQIECIKNALPQNYRSTVQVA 817
            ..:. .|..|..||....:|.|.|.:.|...:..|  .||:.|..|...:.:..    ...|.|.
Worm   193 TAVG-KSFSNEGEARYALQLVEALTRYASTANKKITAAILNFYGAQYSYVYSMA----EDEVTVN 252

  Fly   818 SVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVG 867
            ::|..||.|.::.::.|.||:...|..||..|||:.|||||.:.|..|:|
Worm   253 TIDGCQGQEYDVTIVLLTRSDPYERSKFLVNANRINVALSRPKIATVIIG 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6204	NP_651229.2	AAA_11	449..679	CDD:289831	25/105 (24%)
		AAA_19	467..>513	CDD:289986
		UvrD_C_2	688..869	CDD:304668	53/192 (28%)
R03D7.2	NP_001364577.1	DNA2	<19..302	CDD:224037	72/292 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810