DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHORD and zgc:92429

DIOPT Version :9

Sequence 1:	NP_651226.1	Gene:	CHORD / 42874	FlyBaseID:	FBgn0029503	Length:	354	Species:	Drosophila melanogaster
Sequence 2:	NP_001003457.1	Gene:	zgc:92429 / 445063	ZFINID:	ZDB-GENE-040801-194	Length:	387	Species:	Danio rerio

Alignment Length:	385	Identity:	150/385 - (38%)
Similarity:	211/385 - (54%)	Gaps:	54/385 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 CYNRGCGQLFDPQTNNDESCRHHPGEPFFHDAYKGWSCCNKKSVDFTEFLNIKGCTLAKHSNVKP 68
            |||||||..||...|.|::||.|||.|.||||.||||||.|::.||:|||:|||||..:|||.||
Zfish     5 CYNRGCGDRFDADKNTDDACRFHPGVPIFHDALKGWSCCKKRTTDFSEFLSIKGCTRGRHSNEKP 69

  Fly    69 PEPEKP--------VKDESDKDEVIEVRAPIREAL--PRPPIDSPLTVIQPTVAPALKDMVFAVK 123
            .||.:|        :|.....:|:|.......|||  .||..|.|.|.:|..::|:|..::..::
Zfish    70 EEPLRPEVTSEKGGMKQHGTAEEIIYQGPKSAEALEKERPSSDEPKTKLQVKISPSLIQIMEKME 134

  Fly   124 TPAAQK----SSDAIEVGTTCKNNGCTYSFTGNSSDFGECTYHPGVPIFHEGMKFWSCCQKRTSD 184
            ....:|    .|.|:.||..|||.||..|:.|..::...|.||||.|:||||.|:|:||..:|:|
Zfish   135 ISEREKREKLESQALVVGIKCKNTGCRKSYEGPETNAEICIYHPGAPVFHEGYKYWNCCCIKTTD 199

  Fly   185 FSQFMAQKGCTYGEHKWVKENDDKKVVQCRYDWHQTATNVVMAIYAKKYDYSQSVIELNPIRLHV 249
            |:.|:.|||||.|:|.|:.:.|.|||. ||:|||||.:.||:.||||..:...|.:|.|...|..
Zfish   200 FNAFLDQKGCTSGKHCWIPKQDKKKVA-CRHDWHQTGSQVVVTIYAKNCNPDHSYVEANRTVLTC 263

  Fly   250 NLVFPEQDNARFDLDLELRGIVNVSNASAHMYGTKVEIKLPKLEPGSWSNLNFPNKK-------- 306
            ::.| |.|.. |..|:.|.|:::|.::..:|..:|||:.:.|.:..:|..|..|..|
Zfish   264 HIQF-EGDKV-FHKDIHLWGVIDVKSSLVNMVPSKVEVSMRKADAVAWGKLEDPKHKPEPELTDN 326

  Fly   307 LPVVKKSQV----------------------EEKKKQEESDEEFFD----LD---DIKAE 337
            :...::.:|                      |||||:|:..||..|    |:   |:|.|
Zfish   327 MNSAEQEEVKPQWDISDDDISESDWEDDEEEEEKKKEEKQKEESGDGPPELEQPADVKQE 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHORD	NP_651226.1	CHORD	3..63	CDD:282781	38/58 (66%)
		CHORD	138..199	CDD:282781	31/60 (52%)
		p23_melusin_like	213..301	CDD:107238	31/87 (36%)
zgc:92429	NP_001003457.1	CHORD	3..64	CDD:282781	38/58 (66%)
		CHORD	154..214	CDD:282781	31/59 (53%)
		p23_melusin_like	227..313	CDD:107238	31/87 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573879
Domainoid	1	1.000	102	1.000	Domainoid score	I6787
eggNOG	1	0.900	-	-		E1_KOG1667
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	313	1.000	Inparanoid score	I2556
OMA	1	1.010	-	-		QHG51840
OrthoDB	1	1.010	-	-		D1163528at2759
OrthoFinder	1	1.000	-	-		FOG0002255
OrthoInspector	1	1.000	-	-		otm26435
orthoMCL	1	0.900	-	-		OOG6_102230
Panther	1	1.100	-	-	O	PTHR12621
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1489
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770