Protein Alignment CG5510 and LMAN2

DIOPT Version :10

• Sequence 1: NP_651224.1
• Gene: CG5510 / 42872
• FlyBaseID: FBgn0039160
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_006807.1
• Gene: LMAN2 / 10960
• HGNCID: 16986
• Length: 356
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 159/332 - (47%)
• Similarity: 218/332 - (65%)
• Gaps: 21/332 - (6%)

  Fly    11 LALLALLVAPFVVLGEDMPREPDYMKREHSLVRPFQGVG-VILPHWDFLGNTMVTSNYIRLTPDL 74
            |.||.||.:   |..:......:::||||||::|:|||| ..:|.|||.|:||:||.|:|||||.
Human    33 LFLLLLLGS---VTADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDE 94

  Fly    75 QSKSGALWNYSPVMTRNWEVHVGFKVHGKGTE-LFGDGFAIWYTKERMQTGPVFGSKDHFSGLAI 138
            :||.|::||:.|...::||:||.|||||.|.: |.|||.|:|||::|:..||||||||:|.||||
Human    95 RSKEGSIWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLAI 159

  Fly   139 ILDTYSNHNGPHNHQHPYLSAMVNNGSWSYDHDRDGTHTQLAGCEVRFRNVEYETLVSIRYENDI 203
            .||||.| :.......||:|.||||||.||||.:||..|:||||...|||.:::|.:::||....
Human   160 FLDTYPN-DETTERVFPYISVMVNNGSLSYDHSKDGRWTELAGCTADFRNRDHDTFLAVRYSRGR 223

  Fly   204 LSVSTDLENRNEWKNCFVVANVELPTGYHFGMSATTGDLSDNHDIHSFKFYDLDLNVNH---DEI 265
            |:|.||||::||||||..:..|.|||||:||.||.||||||||||.|.|.:  .|.|.|   :|.
Human   224 LTVMTDLEDKNEWKNCIDITGVRLPTGYYFGASAGTGDLSDNHDIISMKLF--QLMVEHTPDEES 286

  Fly   266 IRRSNIIPNAKTFEPPREHKEDP----KPG-MSNAKIFFILLFV---VVVAAAVAIFAISYFKDR 322
            |..:.|.|:....:.|:::.:||    :.| ::..::|.:||..   :||.|.|.  |:.:.|.:
Human   287 IDWTKIEPSVNFLKSPKDNVDDPTGNFRSGPLTGWRVFLLLLCALLGIVVCAVVG--AVVFQKRQ 349

  Fly   323 NARKRFY 329
            ...||||
Human   350 ERNKRFY 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5510	NP_651224.1	lectin_VIP36_VIPL	34..280	CDD:173889	136/250 (54%)
LMAN2	NP_006807.1	lectin_VIP36_VIPL	53..301	CDD:173889	136/250 (54%)