| Sequence 1: | NP_001334699.1 | Gene: | Apc2 / 42871 | FlyBaseID: | FBgn0026598 | Length: | 1067 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006254568.1 | Gene: | Apc / 24205 | RGDID: | 2123 | Length: | 2870 | Species: | Rattus norvegicus |
| Alignment Length: | 1629 | Identity: | 428/1629 - (26%) |
|---|---|---|---|
| Similarity: | 605/1629 - (37%) | Gaps: | 624/1629 - (38%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 12 ELTRNFLELSRNPETCTALRSSDCIQLLVQILHANDE---------GLSTAKKYASQALHNIVHN 67
Fly 68 NPEEKERQREVKMLRLLDQILDYCNFLHTQLQSGGEAIADDEDRHPL---------AAMKLLMKA 123
Fly 124 SFDEEHRQTMCEL------------------GALKAIPNLVHLDHAVHGPAAGREQCNALRSYGL 170
Fly 171 MALTNLTFGDENVHNKSYLCGQRQFMEVVIAQLNTAPDELLQVLAGVLRNLSWRADKHMKTIFNE 235
Fly 236 LGTVTSLARAAMQNKNENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLK 300
Fly 301 IIENAGGILRNVSSHIAVCEPYRQILRRYNCLAILLQQLKSESLTVVSNSCGTLWNLSARCPEDQ 365
Fly 366 QYLIDHNAIPLLRALISSKNSMIAEGSASALKNLVNFRATQELMPN--GDGGSLP---------- 418
Fly 419 ---LDKE------------------------------------AGHGGTLPRRFSS--------- 435
Fly 436 -----LRLSSNPTGSLKKVR------------------------PSTVSTTGF------------ 459
Fly 460 ----------------------------------------------------LNRKC-------- 464
Fly 465 ---ESRESIYS-------GKSDSTK-----YSTKSEG-----AKNPFEIVTPTE----------- 498
Fly 499 -EQPIDYSMKYMEHKPNSSK---------------------------------TFEI-------- 521
Fly 522 --------------------------------------------------DLDQPTDFSARYKER 536
Fly 537 RSAQ------------------TAQP---ELKSETNEIRSKE--LQLTKSSSA----TELRNSPG 574
Fly 575 LVAVSA--AKQKIATETETETAER-------------PIN------YCEEGTPGSFSRFDSLNSL 618
Fly 619 T-----------------------------------EKPEKCMP---PKTPTKTAVL-------- 637
Fly 638 ---------------PVHVDGNTPQNIDS--ALETPLMFSRRSSMDSLVG-DDETVACEDNGSVI 684
Fly 685 SE-YSRMQSGVISPSELPDSPTQSMPQS-------PRRDRKVSTQNNLDTPEQKPSTVFE----- 736
Fly 737 ------------------DKLNRFHVEHTPAAFSCATSLSNLSM-----------------MDDS 766
Fly 767 NANAIRGQRGNDINGNGDAPRSYCTEDTTAVLSKAPSNSDLSIL------SIPNDLN------AN 819
Fly 820 EAQPVPAPRADVTGMDTRMPAEDAISKM-----RCGGNALPSYLPVSDEMSKYYVEDSPCTFSVI 879
Fly 880 SGLSHLTVGS----AKAGPVLKLPMRTAEEAQAPKLP--------PRRSAVQGDAEPRLPPKKSD 932
Fly 933 SLSSLS---------------------MDSDDDCNLLSQAI-----------AAGSCRPQPSGA- 964
Fly 965 ------STSSSLANASTSTLCRENGQSKKQ-------------------VEHG---DKPN----- 996
Fly 997 ------YSSDDSL-----DDDDDD-ARSKSLFEQCILSGMHKSNDALESEG------EPPGQRQE 1043
Fly 1044 ISAR 1047 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Apc2 | NP_001334699.1 | None | |||
| Apc | XP_006254568.1 | Suppressor_APC | 135..215 | CDD:288297 | |
| ATP-synt_B | <200..283 | CDD:304375 | |||
| ARM | 319..421 | CDD:237987 | 31/83 (37%) | ||
| ARM | 495..623 | CDD:237987 | 62/130 (48%) | ||
| armadillo repeat | 498..534 | CDD:293788 | 14/36 (39%) | ||
| armadillo repeat | 542..579 | CDD:293788 | 16/36 (44%) | ||
| armadillo repeat | 589..621 | CDD:293788 | 15/31 (48%) | ||
| armadillo repeat | 629..670 | CDD:293788 | 28/40 (70%) | ||
| ARM | 637..757 | CDD:237987 | 78/119 (66%) | ||
| armadillo repeat | 679..713 | CDD:293788 | 25/33 (76%) | ||
| armadillo repeat | 721..757 | CDD:293788 | 19/35 (54%) | ||
| Arm_APC_u3 | 758..1045 | CDD:293235 | 35/286 (12%) | ||
| APC_u5 | 1062..1161 | CDD:293236 | 3/98 (3%) | ||
| APC_crr | 1282..>1299 | CDD:283553 | 7/16 (44%) | ||
| APC_u9 | 1308..1393 | CDD:293239 | 7/84 (8%) | ||
| APC_crr | 1663..1687 | CDD:283553 | 9/23 (39%) | ||
| APC_u13 | 1688..1744 | CDD:293240 | 10/55 (18%) | ||
| SAMP | 1745..1764 | CDD:283554 | 1/18 (6%) | ||
| APC_u14 | 1765..1865 | CDD:293241 | 15/99 (15%) | ||
| APC_u15 | 1902..1973 | CDD:293242 | 11/43 (26%) | ||
| SAMP | 2061..2080 | CDD:283554 | |||
| APC_basic | 2251..2596 | CDD:283581 | |||
| EB1_binding | 2698..2870 | CDD:283565 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C166341031 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2122 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002986 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm9133 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105450 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12607 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.700 | |||||