| Sequence 1: | NP_001334699.1 | Gene: | Apc2 / 42871 | FlyBaseID: | FBgn0026598 | Length: | 1067 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_006525592.1 | Gene: | Apc / 11789 | MGIID: | 88039 | Length: | 2870 | Species: | Mus musculus |
| Alignment Length: | 1819 | Identity: | 441/1819 - (24%) |
|---|---|---|---|
| Similarity: | 618/1819 - (33%) | Gaps: | 849/1819 - (46%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 12 ELTRNFLELSRNPETCTALRSSDCIQLLVQILHANDE---------GLSTAKKYASQALHNIVHN 67
Fly 68 NPEEKERQREVKMLRLLDQILDYCNFLHTQLQSGGEAIADDEDRHPL---------AAMKLLMKA 123
Fly 124 SFDEEHRQTMCEL------------------GALKAIPNLVHLDHAVHGPAAGREQCNALRSYGL 170
Fly 171 MALTNLTFGDENVHNKSYLCGQRQFMEVVIAQLNTAPDELLQVLAGVLRNLSWRADKHMKTIFNE 235
Fly 236 LGTVTSLARAAMQNKNENTLKAILSALWNLSAHCSTNKAEFCAVDGALAFLVGMLSYEGPSKTLK 300
Fly 301 IIENAGGILRNVSSHIAVCEPYRQILRRYNCLAILLQQLKSESLTVVSNSCGTLWNLSARCPEDQ 365
Fly 366 QYLIDHNAIPLLRALISSKNSMIAEGSASALKNLVNFRATQELMPN--GDGGSLP---------- 418
Fly 419 ------------------LDKEAGHGGTLPRR---------------------FSS--------- 435
Fly 436 -----LRLSSNPTGSLKKVRP-------------------------------------------- 451
Fly 452 --------------STVSTTGF------------------------------LNRKCE------- 465
Fly 466 ----------------------------------------------------------------- 465
Fly 466 -----------SRESIYSG-----------------------------KSDSTKYSTKSEGA--- 487
Fly 488 ----------------------------------------------KNPFEIVTPT--------- 497
Fly 498 ------EEQPIDYSMKYMEHKPNSSKTFEIDLDQPTDFSARY--------------KERRSAQTA 542
Fly 543 QPELKSETNEIRSKELQLTKSSSATELRNSPGLVAVSAAKQKIATETETETAERPIN------YC 601
Fly 602 EEGTPGSFSRFDSLNSLT-----------------------------------EKPEKCMP---- 627
Fly 628 ------------------------------PKTPTKTAVLPVHVDGNTPQNIDS--ALETPLMFS 660
Fly 661 RRSSMDSLVG-DDETVACEDNGSVISE-YSRMQSGVISPSELPDSPTQSMPQSPRRDRKVSTQNN 723
Fly 724 LDTPEQKPSTVFE-------------------------------------DKLNRFHVEHTPAAF 751
Fly 752 SCATSLSNLS---------------------------------------------------MMDD 765
Fly 766 SN----------------------------------------------------ANAIRGQRGND 778
Fly 779 INGNGDAPRSYCTEDTTAVLSKAPSNSDLSILSIPNDLNANEA-------------QPVP----- 825
Fly 826 ---APRADVTGMDTRMP------AEDAISKMRCGGNALP---SYLP-----VSDEMSKYYVEDSP 873
Fly 874 CTFSVISGLSHLTVGSAK---AGPVLKLPMRTA------------------------EEAQAP-- 909
Fly 910 ---------KLPPRRSAVQG----DAEPRLPP--------KKSDSLSSLSMDSDDDCNLLSQ--- 950
Fly 951 ---------AIAAGSCRPQPS------------------------------------------GA 964
Fly 965 STSSSLAN----------------ASTSTLCRENGQSK-----KQVEHGD------KPNYS---- 998
Fly 999 ------------------SDDSLDDDDDDARSKSLFEQCILSGMHKSN--DALESEGEPPGQRQ 1042 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Apc2 | NP_001334699.1 | None | |||
| Apc | XP_006525592.1 | Suppressor_APC | 135..215 | CDD:371516 | |
| ARM | 348..400 | CDD:214547 | 20/51 (39%) | ||
| APC_rep | 401..474 | CDD:376216 | 25/74 (34%) | ||
| armadillo repeat | 498..534 | CDD:293788 | 13/36 (36%) | ||
| ARM | 538..579 | CDD:214547 | 19/42 (45%) | ||
| armadillo repeat | 542..579 | CDD:293788 | 16/36 (44%) | ||
| armadillo repeat | 589..621 | CDD:293788 | 15/31 (48%) | ||
| armadillo repeat | 629..670 | CDD:293788 | 28/40 (70%) | ||
| ARM | 675..715 | CDD:214547 | 28/39 (72%) | ||
| armadillo repeat | 679..713 | CDD:293788 | 25/33 (76%) | ||
| Arm | 717..755 | CDD:366143 | 19/37 (51%) | ||
| armadillo repeat | 721..757 | CDD:293788 | 19/35 (54%) | ||
| Arm_APC_u3 | 758..1045 | CDD:374686 | 25/286 (9%) | ||
| APC_u5 | 1062..1161 | CDD:374687 | 7/98 (7%) | ||
| APC_r | 1283..>1300 | CDD:368672 | 7/16 (44%) | ||
| APC_u9 | 1309..1395 | CDD:374689 | 6/92 (7%) | ||
| APC_r | 1663..1686 | CDD:368672 | 11/22 (50%) | ||
| APC_u13 | 1688..1741 | CDD:374690 | 10/54 (19%) | ||
| SAMP | 1742..1763 | CDD:368673 | 5/20 (25%) | ||
| APC_u14 | 1772..1865 | CDD:374691 | 16/100 (16%) | ||
| APC_u15 | 1899..1973 | CDD:374692 | 8/73 (11%) | ||
| SAMP | 2060..2079 | CDD:368673 | 9/24 (38%) | ||
| APC_basic | 2251..2596 | CDD:368684 | |||
| EB1_binding | 2698..2870 | CDD:368678 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167837311 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2122 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002986 | |
| OrthoInspector | 1 | 1.000 | - | - | mtm8887 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_105450 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12607 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2401 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 10 | 9.730 | |||||