Protein Alignment CG6178 and menE

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_416763.1
• Gene: menE / 946741
• ECOCYCID: EG12437
• Length: 451
• Species: Escherichia coli
• Alignment Length: 496
• Identity: 116/496 - (23%)
• Similarity: 190/496 - (38%)
• Gaps: 119/496 - (23%)

  Fly    73 GVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDR 137
            ||.:...|.|.:.|:....||..|.|..||.|.|:|.           .|.:|.
E. coli    48 GVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNP-----------QLPQPL----------- 90

  Fly   138 VAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMED--EKFKTQPD--FTSPAANKDEDVSLI-- 196
                                         |:||:.:  .:|...||  .|.||.. ...:.|:
E. coli    91 -----------------------------LEELLPNLTLQFALVPDGENTFPALT-SLHIQLVEG 125

  Fly   197 ----------VCS----SGTTGLPKGVQLTQMNLLATLDSQIQPTVIPM-EEVTLLTVIPWFHAF 246
                      :||    ||:|||||....|....||:....:  ::||. :....|..:|.||..
E. coli   126 AHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHLASAQGVL--SLIPFGDHDDWLLSLPLFHVS 188

  Fly   247 GCLTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVL 311
            |...:......|||:....|...:..|:....     |.:||..:..|    :|::..:|...||
E. coli   189 GQGIMWRWLYAGARMTVRDKQPLEQMLAGCTH-----ASLVPTQLWRL----LVNRSSVSLKAVL 244

  Fly   312 LCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPD 376
            |.||| :..|..:|.:|: |:... .||||:|...:|       |...:.|:..||      .|.
E. coli   245 LGGAA-IPVELTEQAREQ-GIRCF-CGYGLTEFASTV-------CAKEADGLADVG------SPL 293

  Fly   377 TG---KLLGANERGELCFKGDGIMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKE 438
            .|   |::    ..|:..:...:.:||..:.:.......:||..|.|.|...:. :..||.|:..
E. coli   294 PGREVKIV----NNEVWLRAASMAEGYWRNGQLVSLVNDEGWYATRDRGEMHNG-KLTIVGRLDN 353

  Fly   439 LIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFV-VKQANVQLTENEVIQFVND 502
            |....|..:.|.|:|.::..:..:....::...|:|.|..|:|.: ....:|.|:|     :|.|
E. coli   354 LFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEYDHESVDLSE-----WVKD 413

  Fly   503 NASPAKRLRGGVIFVDEIP--KNPSGKILRRILREMLKKQK 541
            ..:   |.:..|.::...|  ||...||.|:.|:|.:::|:
E. coli   414 KLA---RFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQQ 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	114/489 (23%)
menE	NP_416763.1	PRK09029	1..451	CDD:236363	115/494 (23%)