Protein Alignment CG6178 and caiC

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_414579.4
• Gene: caiC / 944886
• ECOCYCID: EG11558
• Length: 517
• Species: Escherichia coli
• Alignment Length: 575
• Identity: 154/575 - (26%)
• Similarity: 250/575 - (43%)
• Gaps: 111/575 - (19%)

  Fly    11 VYGGPVTERQAQDSRSLGQYILDKYKSFGDRTVLV-DAVNGV--EYSASFMHKSIVRLAYILQKL 72
            :.||       |..|.:...:.|.|   |.:|.|: ::..||  .||...:::.|.|.|.:...|
E. coli     3 IIGG-------QHLRQMWDDLADVY---GHKTALICESSGGVVNRYSYLELNQEINRTANLFYTL 57

  Fly    73 GVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDR 137
            |:::.|.|.|..:|...|....|....:||.:.|:|                      :::..:.
E. coli    58 GIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPIN----------------------ARLLCEE 100

  Fly   138 VAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDE------------------------KFKT 178
            .|.:...::     ..|..||.:|..:|  :::.:::                        :.|.
E. coli   101 SAWILQNSQ-----ACLLVTSAQFYPMY--QQIQQEDATQLRHICLTDVALPADDGVSSFTQLKN 158

  Fly   179 QPDFT---SPAANKDEDVSLIVCSSGTTGLPKGVQLTQMNL-LATLDSQIQPTVIPMEEVTLLTV 239
            |...|   :|..:.| |.:.|:.:||||..||||.:|..|| .|...|..|..:  .::...|||
E. coli   159 QQPATLCYAPPLSTD-DTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCAL--RDDDVYLTV 220

  Fly   240 IPWFHA-FGCLTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIV--- 300
            :|.||. ..|...:.....||..|.:.|:..:.|...::|||..:...:|.::..|...|..
E. coli   221 MPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATVTECIPMMIRTLMVQPPSAND 285

  Fly   301 DKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPG------ 359
            .::.|..:|..|    .||.:.:|...||.||..: ..||::|:.:.::..     :||
E. coli   286 QQHRLREVMFYL----NLSEQEKDAFCERFGVRLL-TSYGMTETIVGIIGD-----RPGDKRRWP 340

  Fly   360 SVGVLKVGI-YAKVIDPDTGKLLGANERGELCFK---GDGIMKGYIGDTKSTQTAIK-DGWLHTG 419
            |:|  :||. |...|..|..:.|.|.|.||:|.|   |..|.|.|..:.::|...:: |||||||
E. coli   341 SIG--RVGFCYEAEIRDDHNRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAKVLEADGWLHTG 403

  Fly   420 DIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVV 484
            |.||.|::..|:.|||...:||..|..|...|:|.::..:.||:|..|:|..|....|...||||
E. coli   404 DTGYRDEEDFFYFVDRRCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDEAIKAFVV 468

  Fly   485 KQANVQLTENEVIQFVNDNASPAK-----RLRGGVIFVDEIPKNPSGKILRRILR 534
            ......|:|.|..:|...|.:..|     .:|      .::|:|.||||:|:.|:
E. coli   469 LNEGETLSEEEFFRFCEQNMAKFKVPSYLEIR------KDLPRNCSGKIIRKNLK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	154/575 (27%)
caiC	NP_414579.4	caiC	1..517	CDD:181195	153/573 (27%)