Protein Alignment CG6178 and PCS60

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_009781.3
• Gene: PCS60 / 852523
• SGDID: S000000426
• Length: 543
• Species: Saccharomyces cerevisiae
• Alignment Length: 500
• Identity: 137/500 - (27%)
• Similarity: 241/500 - (48%)
• Gaps: 44/500 - (8%)

  Fly    74 VKQNDVVGLSSENSVNFALAMFAGLAVGATV-APLNVTYSDREVDHAINLSKPKIIF----ASKI 133
            |.:.|.|.:|..|.:.|.:| |.|..:.|.: ||||..|.::|.:..:|..|.|.|.    .:|:
Yeast    59 VFRQDTVAISMRNGLEFIVA-FLGATMDAKIGAPLNPNYKEKEFNFYLNDLKSKAICVPKGTTKL 122

  Fly   134 TIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDL-------KEL----MEDEKFKTQPDFTSPAA 187
            ....:.|.||  .|...|:.|:..:.:|:..||:       |.:    :.:.||........|..
Yeast   123 QSSEILKSAS--TFGCFIVELAFDATRFRVEYDIYSPEDNYKRVIYRSLNNAKFVNTNPVKFPGF 185

  Fly   188 NKDEDVSLIVCSSGTTGLPKGVQLTQMNLL-ATLDSQIQPTVIPMEEVTLLTVIPWFHAFGCL-T 250
            .:..||:||:.:||||..||.|.|..:|:: :||:......:.|::.  ...|:|.||..|.: .
Yeast   186 ARSSDVALILHTSGTTSTPKTVPLLHLNIVRSTLNIANTYKLTPLDR--SYVVMPLFHVHGLIGV 248

  Fly   251 LITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGA 315
            |::|......:|....|..|||.....||.......||.:.:.:...|..:.:. ....:..|.:
Yeast   249 LLSTFRTQGSVVVPDGFHPKLFWDQFVKYNCNWFSCVPTISMIMLNMPKPNPFP-HIRFIRSCSS 312

  Fly   316 APLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQN--DEFCKPGSVGVLKVGIYAKVIDPDTG 378
            | |:..|..::::....| :.:.|.::|::..:...|  ....|||:||..: |:...::| |..
Yeast   313 A-LAPATFHKLEKEFNAP-VLEAYAMTEASHQMTSNNLPPGKRKPGTVGQPQ-GVTVVILD-DND 373

  Fly   379 KLLGANERGELCFKGDGIMKGYIGDTKSTQTAI--KDGWLHTGDIGYYDDDFEFFIVDRIKELIK 441
            .:|...:.||:..:|:.:..||..:.|:.:...  ::.:..|||.||:|.:....:..||||||.
Yeast   374 NVLPPGKVGEVSIRGENVTLGYANNPKANKENFTKRENYFRTGDQGYFDPEGFLVLTGRIKELIN 438

  Fly   442 YKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNAS- 505
            ..|.::.|.|::.::|::.||.:|...|.||:..|::..|.:|.:...::|..|::.|:..:.:
Yeast   439 RGGEKISPIELDGIMLSHPKIDEAVAFGVPDDMYGQVVQAAIVLKKGEKMTYEELVNFLKKHLAS 503

  Fly   506 ---PAKRLRGGVIFVDEIPKNPSGKILRRILREMLKK---QKSKL 544
               |.|     |.|||::||..:|||.||::.|...|   .||||
Yeast   504 FKIPTK-----VYFVDKLPKTATGKIQRRVIAETFAKSSRNKSKL 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	131/487 (27%)
PCS60	NP_009781.3	FACL_fum10p_like	18..531	CDD:341249	131/486 (27%)