DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and 4CL3

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_176686.1	Gene:	4CL3 / 842814	AraportID:	AT1G65060	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	190/522 - (36%)
Similarity:	290/522 - (55%)	Gaps:	22/522 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLGVKQNDVVGLSSENSVNFA 91
            |..|..:|..|..|:..|:....|..|:....|....|:|..|.|||:::.||:.:..:||..|.
plant    50 LHTYCFEKLSSVSDKPCLIVGSTGKSYTYGETHLICRRVASGLYKLGIRKGDVIMILLQNSAEFV 114

  Fly    92 LAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALSG 156
            .:......:||.....|..|:.:|:...:..|..|:|......:|::..:.      :.:..::.
plant   115 FSFMGASMIGAVSTTANPFYTSQELYKQLKSSGAKLIITHSQYVDKLKNLG------ENLTLITT 173

  Fly   157 TSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKGVQLTQMNLLATLD 221
            .....:|......|:.|:  :|.| |........:|.:.:..|||||||||||.||..:|:.::.
plant   174 DEPTPENCLPFSTLITDD--ETNP-FQETVDIGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVA 235

  Fly   222 SQI---QPTVIPMEEVTLLTVIPWFHAFGC-LTLITTACVGARLVYLPKFEEKLFLSAIEKYRVM 282
            .|:   .|.:.......:|.|:|.||.:.. ..|:.:...||.::.:.|||....|..|:::||.
plant   236 QQVDGDNPNLYLKSNDVILCVLPLFHIYSLNSVLLNSLRSGATVLLMHKFEIGALLDLIQRHRVT 300

  Fly   283 MAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLS 347
            :|.:||||::.|||:|.|:.|||||:..:|.|||||.:|.:|.::.|:....:.||||::|:. .
plant   301 IAALVPPLVIALAKNPTVNSYDLSSVRFVLSGAAPLGKELQDSLRRRLPQAILGQGYGMTEAG-P 364

  Fly   348 VLVQNDEFC------KPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGDTKS 406
            ||..:..|.      |.||.|.:......||:..:|...||.|:.||:|.:|..|||.|:.|.::
plant   365 VLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEA 429

  Fly   407 TQTAI-KDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGK 470
            |...| ::||||||||||.|:|.|.|||||:||:||:||:||||||:|:||:.:..|.||||:.:
plant   430 TSATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQ 494

  Fly   471 PDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILRE 535
            .||.|||:|:||||:.....:||.:|.::|.......|||. .|.||..|||:|||||||:.|:.
plant   495 NDEVAGEVPVAFVVRSNGNDITEEDVKEYVAKQVVFYKRLH-KVFFVASIPKSPSGKILRKDLKA 558

  Fly   536 ML 537
            .|
plant   559 KL 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	189/520 (36%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	180/496 (36%)
4CL3	NP_176686.1	PLN02246	26..561	CDD:215137	190/522 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I559
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	334	1.000	Inparanoid score	I670
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		otm2541
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.880