DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and 4CL1

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_175579.1	Gene:	4CL1 / 841593	AraportID:	AT1G51680	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	199/555 - (35%)
Similarity:	298/555 - (53%)	Gaps:	45/555 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NIVYGGPVTERQAQDSRSLGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLG 73
            ::::...:.:....:..||..||......|..:..|::...|..|:.|.:|....::|....|||
plant    22 DVIFRSKLPDIYIPNHLSLHDYIFQNISEFATKPCLINGPTGHVYTYSDVHVISRQIAANFHKLG 86

  Fly    74 VKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRV 138
            |.|||||.|...|...|.|:..|....|||....|..::..|:......|..|:|......:|::
plant    87 VNQNDVVMLLLPNCPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNTKLIITEARYVDKI 151

  Fly   139 AKVASKNKFV-------------KGII---ALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAA 187
            ..:.:.:..|             :|.:   .|:.::.:...:.|..|:..|
plant   152 KPLQNDDGVVIVCIDDNESVPIPEGCLRFTELTQSTTEASEVIDSVEISPD-------------- 202

  Fly   188 NKDEDVSLIVCSSGTTGLPKGVQLTQMNLLATLDSQI---QPTVIPMEEVTLLTVIPWFHAFGCL 249
                ||..:..|||||||||||.||...|:.::..|:   .|.:....:..:|.|:|.||.:...
plant   203 ----DVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALN 263

  Fly   250 TLITTAC-VGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLC 313
            :::.... |||.::.:||||..|.|..|::.:|.:|.||||:::.:||....:||||||:.|:..
plant   264 SIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPMVPPIVLAIAKSSETEKYDLSSIRVVKS 328

  Fly   314 GAAPLSRETEDQIKERIGVPFIRQGYGLSES----TLSVLVQNDEF-CKPGSVGVLKVGIYAKVI 373
            |||||.:|.||.:..:.....:.||||::|:    .:|:....:.| .|.|:.|.:......|::
plant   329 GAAPLGKELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIV 393

  Fly   374 DPDTGKLLGANERGELCFKGDGIMKGYIGDTKST-QTAIKDGWLHTGDIGYYDDDFEFFIVDRIK 437
            |||||..|..|:.||:|.:|..|||||:.:..:| :|..|||||||||||..|||.|.|||||:|
plant   394 DPDTGDSLSRNQPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLK 458

  Fly   438 ELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVND 502
            |||||||:||.|||:||||:.:..|.|.||:...:|.|||:|:|||||..:.:|:|::|.|||:.
plant   459 ELIKYKGFQVAPAELEALLIGHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELSEDDVKQFVSK 523

  Fly   503 NASPAKRLRGGVIFVDEIPKNPSGKILRRILREML 537
            .....||: ..|.|.:.|||.|||||||:.||..|
plant   524 QVVFYKRI-NKVFFTESIPKAPSGKILRKDLRAKL 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	198/536 (37%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	188/511 (37%)
4CL1	NP_175579.1	PLN02246	16..560	CDD:215137	199/555 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I559
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	334	1.000	Inparanoid score	I670
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		otm2541
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.880