DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6178 and AAE14

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001322322.1	Gene:	AAE14 / 839932	AraportID:	AT1G30520	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	523	Identity:	134/523 - (25%)
Similarity:	234/523 - (44%)	Gaps:	61/523 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 IVRLAYILQKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPK 126
            ::.||..|.:||::..|||.:::.||..|...:.|...||..|||||..:|.:|...|:.|.:|.
plant    42 VLSLAAGLIRLGLRNGDVVSIAAFNSDLFLEWLLAVALVGGVVAPLNYRWSLKEAKMAMLLVEPV 106

  Fly   127 IIFASKITIDRVAKVASKN-KFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQ---PDFTSPAA 187
            ::...:..:.....|.:.: ..:|..:.:..||..|.|  :|.:.:..|..|.:   |...:.|.
plant   107 LLVTDETCVSWCIDVQNGDIPSLKWRVLMESTSTDFAN--ELNQFLTTEMLKQRTLVPSLATYAW 169

  Fly   188 NKDEDVSLIVC-SSGTTGLPKGVQLTQMNLLATLDSQIQPTVIPMEEVTLLTVIPWFHAFGCLTL 251
            ..|:  ::::| :|||||.||||.::.:..:....::|.......::|.|.| .|..|..|..:.
plant   170 ASDD--AVVICFTSGTTGRPKGVTISHLAFITQSLAKIAIAGYGEDDVYLHT-SPLVHIGGLSSA 231

  Fly   252 ITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMV--LLCG 314
            :....|||..|.||||:.|..|..:|:..:.....||.:|..|.:.....|....:..|  :|.|
plant   232 MAMLMVGACHVLLPKFDAKTALQVMEQNHITCFITVPAMMADLIRVNRTTKNGAENRGVRKILNG 296

  Fly   315 AAPLSRETEDQIKERIGV-PFIR--QGYGLSE--STLSVLVQNDEFCKPGSVGVLKVGIYAKVID 374
            ...||.|.   :||.:.: |..|  ..||::|  |:|:.:..:|...:...|      .|..:..
plant   297 GGSLSSEL---LKEAVNIFPCARILSAYGMTEACSSLTFMTLHDPTQESFKV------TYPLLNQ 352

  Fly   375 PDTGKLLG---------------ANERGELCFKGDGIMKGYIG------DTKSTQTAIKDGWLHT 418
            |..|..:|               ::..|::..:|...|..|.|      :.:::::...:.||.|
plant   353 PKQGTCVGKPAPHIELMVKLDEDSSRVGKILTRGPHTMLRYWGHQVAQENVETSESRSNEAWLDT 417

  Fly   419 GDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFV 483
            ||||.:|:....:::.|....||..|..|.|.|:||:|:.:..|..|.|||..|...||:.:|.|
plant   418 GDIGAFDEFGNLWLIGRSNGRIKTGGENVYPEEVEAVLVEHPGIVSAVVIGVIDTRLGEMVVACV 482

  Fly   484 ------------VKQANVQLTENEVIQFV-NDNASPAKRLRGGVIFVDEIPKNPSGKILR-RILR 534
                        .::.:.||:...:.... ..|.:..|..:..|.:..:.|...:||:.| .:.|
plant   483 RLQEKWIWSDVENRKGSFQLSSETLKHHCRTQNLTGFKIPKRFVRWEKQFPLTTTGKVKRDEVRR 547

  Fly   535 EML 537
            ::|
plant   548 QVL 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	133/521 (26%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	131/512 (26%)
AAE14	NP_001322322.1	PLN02860	1..560	CDD:215464	134/523 (26%)
		AFD_class_I	42..>269	CDD:302604	65/231 (28%)
		AFD_class_I	172..546	CDD:302604	97/385 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810