DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6178 and AT1G20500

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_173474.5	Gene:	AT1G20500 / 838638	AraportID:	AT1G20500	Length:	550	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	184/526 - (34%)
Similarity:	288/526 - (54%)	Gaps:	49/526 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RTVLVDAVNGVEYSASFMHKSIVRLAYIL-QKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATV 104
            :|..:||..|...:.|.:.:::.|:|..| .::|:::.|||.:.|.||:...:...:.:::||..
plant    52 KTAFIDAATGQCLTFSDLWRAVDRVADCLYHEVGIRRGDVVLILSPNSIFIPVVCLSVMSLGAVF 116

  Fly   105 APLNVTYSDREVDHAINLSKPKIIFASK-------------ITIDRVAKVASKNKFVKGIIALSG 156
            ...|...:..|:...|..|.|.::|.::             :|.|.|.:..:....|.||::
plant   117 TTANTLNTSGEISKQIADSNPTLVFTTRQLAPKLPVAISVVLTDDEVYQELTSAIRVVGILS--- 178

  Fly   157 TSKKFKNIYDLKELMEDEKFKTQP--DFTSPAANKDEDVSLIVCSSGTTGLPKGVQLTQMNLLAT 219
                             |..|.:|  .......|:| |.::::.||||||..|||..:..||.|.
plant   179 -----------------EMVKKEPSGQRVRDRVNQD-DTAMMLYSSGTTGPSKGVISSHRNLTAH 225

  Fly   220 LDSQIQPTVIPMEEVTLLTVIPWFHAFGCLTL-ITTACVGARLVYLPKFEEKLFLSAIEKYRVMM 283
            :...|... :..:::.:.|| |.||.:|.||. :.|..:|:.:|.|.:|:....:.|:||:|...
plant   226 VARFISDN-LKRDDIFICTV-PMFHTYGLLTFAMGTVALGSTVVILRRFQLHDMMDAVEKHRATA 288

  Fly   284 AFMVPPLMVFLAKHP--IVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTL 346
            ..:.||::|.:....  |..|||||||..:.||.||||:|..:...|:.....|.|||.|:||..
plant   289 LALAPPVLVAMINDADLIKAKYDLSSLKTVRCGGAPLSKEVTEGFLEKYPTVDILQGYALTESNG 353

  Fly   347 SVLVQN--DEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGDTKSTQT 409
            .....|  :|..:.|:.|.|...:.|:::||:||:.:|.|:.|||..||..|.|||..:.::|..
plant   354 GGAFTNSAEESRRYGTAGTLTSDVEARIVDPNTGRFMGINQTGELWLKGPSISKGYFKNQEATNE 418

  Fly   410 AIK-DGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDE 473
            .|. :|||.|||:.|.|:|...|:|||:|||||||||||||||:||||:|:..|.|||||..||:
plant   419 TINLEGWLKTGDLCYIDEDGFLFVVDRLKELIKYKGYQVPPAELEALLITHPDILDAAVIPFPDK 483

  Fly   474 EAGELPLAFVVKQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREMLK 538
            |||:.|:|:||::....|:|.:||.|::...:|.|::| .|.|::.|||..|||.||   ::::|
plant   484 EAGQYPMAYVVRKHESNLSEKQVIDFISKQVAPYKKIR-KVSFINSIPKTASGKTLR---KDLIK 544

  Fly   539 KQKSKL 544
            ...|||
plant   545 LATSKL 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	180/517 (35%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	177/507 (35%)
AT1G20500	NP_173474.5	PLN02574	16..542	CDD:215312	180/516 (35%)
AT1G20500	NP_173474.5	4CL	32..542	CDD:213272	180/516 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3017
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2541
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.830