DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and AT5G63380

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_201143.1	Gene:	AT5G63380 / 836457	AraportID:	AT5G63380	Length:	562	Species:	Arabidopsis thaliana

Alignment Length:	571	Identity:	197/571 - (34%)
Similarity:	302/571 - (52%)	Gaps:	75/571 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QAQDSRSLGQYILDKYKSFGDRTVLVDA-------------VNGVEYSASFMHKS---------I 62
            :..|||     ::|:...|..||.:..:             ::..|::.|.:.||         |
plant     4 KTNDSR-----LIDRSSGFDQRTGIYHSLRPSLSLPPIDQPLSAAEFALSLLLKSSPPATAGKNI 63

  Fly    63 VRLAYI-----------------LQKLGVK---------QNDVVGLSSENSVNFALAMFAGLAVG 101
            ..|.|:                 ::.|.|.         ..:|..:.|.:|::..:...|.:::|
plant    64 EALTYLVNSSSGDNLTYGELLRRVRSLAVSLRERFPSLASRNVAFILSPSSLDIPVLYLALMSIG 128

  Fly   102 ATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYD 166
            ..|:|.|...|:.||.|.:.:|:|.|.||:..|:    |....:....|.:.:..|  :|.:..:
plant   129 VVVSPANPIGSESEVSHQVEVSEPVIAFATSQTV----KKLQSSSLPLGTVLMDST--EFLSWLN 187

  Fly   167 LKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKGVQLTQMNLLATLDSQIQPTV--- 228
            ..:......|:.|.:.:.|||        |:.||||||..|||.||..||:|:.....|.|:
plant   188 RSDSSSVNPFQVQVNQSDPAA--------ILFSSGTTGRVKGVLLTHRNLIASTAVSHQRTLQDP 244

  Fly   229 IPMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVF 293
            :..:.|.|.: :|.||.||.:.:|....:|..||.|.:||.:....|:|||:|....:.|||:|.
plant   245 VNYDRVGLFS-LPLFHVFGFMMMIRAISLGETLVLLGRFELEAMFKAVEKYKVTGMPVSPPLIVA 308

  Fly   294 LAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSEST--LSVLVQNDEFC 356
            |.|..:..||||.||..|.||.|||.::..::.|::.....|.|||||:||:  .:.....:|..
plant   309 LVKSELTKKYDLRSLRSLGCGGAPLGKDIAERFKQKFPDVDIVQGYGLTESSGPAASTFGPEEMV 373

  Fly   357 KPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGDTK-STQTAIKDGWLHTGD 420
            |.||||.:...:.||::||.||:.|...:.|||..:|..|||||:|:.| |.:|..|:|||.|||
plant   374 KYGSVGRISENMEAKIVDPSTGESLPPGKTGELWLRGPVIMKGYVGNEKASAETVDKEGWLKTGD 438

  Fly   421 IGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVK 485
            :.|:|.:...:||||:|||||||.|||||.|:|.:|.:|..:.||||:..|||:|||:|:||:|:
plant   439 LCYFDSEDFLYIVDRLKELIKYKAYQVPPVELEQILHSNPDVIDAAVVPFPDEDAGEIPMAFIVR 503

  Fly   486 QANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREM 536
            :....|.|.::|.||....:|.|::| .|.|::.|||||:||||||.|.::
plant   504 KPGSNLNEAQIIDFVAKQVTPYKKVR-RVAFINAIPKNPAGKILRRELTKI 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	194/565 (34%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	185/539 (34%)
AT5G63380	NP_201143.1	PLN02574	17..562	CDD:215312	193/553 (35%)
AT5G63380	NP_201143.1	4CL	48..550	CDD:213272	188/517 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I3017
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H135369
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		otm2541
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.920