Protein Alignment CG6178 and ACSM5

DIOPT Version :9

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001311301.1
• Gene: ACSM5 / 54988
• HGNCID: 26060
• Length: 582
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 124/575 - (21%)
• Similarity: 232/575 - (40%)
• Gaps: 101/575 - (17%)

  Fly    15 PVTER--QAQDSRSLGQYILDKYKSFGDRTV-----LVDA-----------VNG----VEYSASF 57
            ||.::  ...::.|||:.::.:|.:|....:     |.:|           |||    :::|...
Human    30 PVPQKIVATWEAISLGRQLVPEYFNFAHDVLDVWSRLEEAGHRPPNPAFWWVNGTGAEIKWSFEE 94

  Fly    58 MHKSIVRLAYIL-QKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAIN 121
            :.|...:.|.:| ...|::..|.:.|.......:.|...|.:..|..:.|.....:::::.:.:.
Human    95 LGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQLTEKDLKYRLQ 159

  Fly   122 LSKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPA 186
            .|:.|.|..|.....||..::::...::..:.:|.:|:  ....:.:||:.:         .|..
Human   160 ASRAKSIITSDSLAPRVDAISAECPSLQTKLLVSDSSR--PGWLNFRELLRE---------ASTE 213

  Fly   187 AN----KDEDVSLIVCSSGTTGLPKGVQLTQMNL-----------LATLDSQIQPTVIPMEEVTL 236
            .|    |..|...|..:|||||.||.|:.:|.:.           :|..:|.|         ...
Human   214 HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWVALTESDI---------FWN 269

  Fly   237 LTVIPWFHAFGCLTLITT----ACVGARLVY-LPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAK 296
            .|...|..|  ..||.:.    :|:   .|: ||:.:.|:.|:.:.|:.:.....||.:...|.:
Human   270 TTDTGWVKA--AWTLFSAWPNGSCI---FVHELPRVDAKVILNTLSKFPITTLCCVPTIFRLLVQ 329

  Fly   297 HPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSV 361
            ..:. :|...||...|.|...|:.:..::.|.:.||. :.:|||.||:.:..........|.||:
Human   330 EDLT-RYQFQSLRHCLTGGEALNPDVREKWKHQTGVE-LYEGYGQSETVVICANPKGMKIKSGSM 392

  Fly   362 GVLKVGIYAKVIDPDTGKLLGANERGEL----------CFKGDGIMKGYIGDTKSTQTAIKDGWL 416
            |........:::| |.|.:|...|.|.:          ||     ...|:.:.:.|..:.:..:.
Human   393 GKASPPYDVQIVD-DEGNVLPPGEEGNVAVRIRPTRPFCF-----FNCYLDNPEKTAASEQGDFY 451

  Fly   417 HTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLA 481
            .|||....|.|..|:.:.|..::|....|::.|.|:|:.|..:..:.::||:..||...||:..|
Human   452 ITGDRARMDKDGYFWFMGRNDDVINSSSYRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKA 516

  Fly   482 FVV-----KQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRR 531
            |:|     ...:.:....|:.:.|....:|.|..|          ||...:.|.|
Human   517 FIVLTPAYSSHDPEALTRELQEHVKRVTAPYKYPR----------KNCQRRFLER 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	122/562 (22%)
		Firefly_Luc_like	43..529	CDD:213279	115/541 (21%)
ACSM5	NP_001311301.1	Acs	49..552	CDD:223442	115/545 (21%)
		AFD_class_I	49..552	CDD:302604	115/545 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920