DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and CG4830

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_650160.1	Gene:	CG4830 / 41477	FlyBaseID:	FBgn0037996	Length:	534	Species:	Drosophila melanogaster

Alignment Length:	533	Identity:	157/533 - (29%)
Similarity:	248/533 - (46%)	Gaps:	23/533 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NIVYGGPVTERQAQDSRSLGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLG 73
            |.::.|.......:...|||:.|....:::......:....|||.:........:|:|..|:..|
  Fly    12 NKIWKGIPQNNPFKPETSLGRIIFKNMRNWPKNVCQISDSEGVEVTFGQALTWAIRIAQQLKSRG 76

  Fly    74 VKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRV 138
            :...|::|:|:.|:........|....|......|....:..:.|..|:|||||||......|::
  Fly    77 LDHKDIIGISARNTTYIMPTAVACFFHGTPFQSANPILEESTLKHLYNISKPKIIFTDADHYDKL 141

  Fly   139 AKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTT 203
            ....|  .|...||..:||.....:|.||....:.| |..||   :|..........|:.|||||
  Fly   142 YSATS--AFKPEIILTTGTKDGVLSIQDLLAPTKTE-FFYQP---TPLKEGPSQTVAILTSSGTT 200

  Fly   204 GLPKGVQLTQMNLLATLDSQIQPTVI--PMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPK 266
            |:||.|.::.       |...|.||.  ..:.:.:...:.|...... |:.:|.....|::....
  Fly   201 GMPKAVCISN-------DILTQETVFVNGYDTIFISASLDWITGLWA-TIFSTVNGCTRIISSKP 257

  Fly   267 FEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIG 331
            |....|:..:.||.:..|.:.|.....|...|......|.||..|..|...:::.|.:::|:...
  Fly   258 FAADYFVYLVSKYSITYALIPPEHCCSLLDCPTATPEKLGSLTKLNFGGGRMTQATVERVKKLAP 322

  Fly   332 VPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGI 396
            ...:...||::|  :..:|.|....|..:.|....||..|::| |.|..||.|:.||:.......
  Fly   323 NGVLNSSYGMTE--VGFIVFNHGHLKLTAAGNPLPGIQVKIVD-DDGNQLGVNQTGEIIVHNGFS 384

  Fly   397 MKGYIGDTKSTQTAIKD--GWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTN 459
            ..||..|.::|: |::|  ||.||||:||:|:|...::.||.||::|:||.|:.|||:||::...
  Fly   385 WNGYFADPEATK-AMQDEEGWFHTGDMGYFDEDDYLYMTDRKKEVLKWKGLQMWPAEVEAVIDEL 448

  Fly   460 DKIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASP-AKRLRGGVIFVDEIPKN 523
            .::|...|||..||..|::|.|.||::.|..||..:||..|...... .|:||.||.|.||||:|
  Fly   449 PEVKRVCVIGVYDETQGDVPGALVVREDNATLTAQQVIDHVAKRLPDIQKQLRAGVQFADEIPQN 513

  Fly   524 PSGKILRRILREM 536
            .:||::||..|::
  Fly   514 HNGKVVRRYARDL 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	155/516 (30%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	148/490 (30%)
CG4830	NP_650160.1	CaiC	18..529	CDD:223395	155/527 (29%)
CG4830	NP_650160.1	AFD_class_I	46..518	CDD:302604	147/489 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D683933at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920