DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6178 and Acsm1

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001101972.2	Gene:	Acsm1 / 361638	RGDID:	1306813	Length:	577	Species:	Rattus norvegicus

Alignment Length:	484	Identity:	120/484 - (24%)
Similarity:	212/484 - (43%)	Gaps:	36/484 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 QKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKIT 134
            |..|::..|.:.|.......:.|.....:..|....|.......:::.:.|.:|:.|.|..:...
  Rat   104 QTCGLQHGDRLALILPRVPEWWLVTVGCIRTGVIFIPGTAQMKAKDILYRIQMSQAKAIVTTDSL 168

  Fly   135 IDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCS 199
            :..|..|||:...:|..|.:|  ....:...:.:.|:.    ...||.|. ..:|.:|..:|..:
  Rat   169 VPEVESVASECPGLKTKIVVS--DHNHEGWLNFRTLLR----SASPDHTC-VKSKMKDPMVIFFT 226

  Fly   200 SGTTGLPKGVQLTQ-MNLLATLDSQIQPTVIPMEEVTLLTVIP-WFHA-FGCLTLITTACVGARL 261
            |||||.||..:..| :...:::.|..:...:...:|......| |..| .|||....||.....:
  Rat   227 SGTTGYPKMAKHNQGLAFRSSVPSCRKFLKLKTSDVIWCMSDPGWILATVGCLLEPWTAGATVFV 291

  Fly   262 VYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMV-----LLCGAAPLSRE 321
            ..||:|:.|:.:..:.||.:......|      |.:.:|.:.::|:|..     ...|...|..|
  Rat   292 HNLPQFDPKVIVETLFKYPITQCLAAP------AVYRMVLQKNISNLRFPTLEHCATGGESLLPE 350

  Fly   322 TEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANER 386
            ..:|.|:|.|:. |.:.||.||:.::..:..:...|.||:|...:....::|| :.|.:|..|..
  Rat   351 EYEQWKQRTGLS-IHEVYGQSETGITCAIFREMKVKRGSIGKAILPFDIQIID-EKGNILPPNTE 413

  Fly   387 GELCFKGD-----GIMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQ 446
            |.:..:..     |:..||....:.|.......:.::||....|:|...:.:.|..::|...||:
  Rat   414 GYIGIRIKPTRPLGLFVGYENSPEKTSEVECGDFYNSGDRATIDEDGYIWFLGRSDDVINASGYR 478

  Fly   447 VPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVV------KQANVQLTENEVIQFVNDNAS 505
            :.|.|:|..|:.:..:.::||:..||::.||:..||:|      .....||.: |:.:.|....:
  Rat   479 IGPTEVENALVEHPAVSESAVVSSPDKDRGEVVKAFIVLNPEFLSHDQEQLIK-ELQEHVKSVTA 542

  Fly   506 PAKRLRGGVIFVDEIPKNPSGKILRRILR 534
            |.|..| .|.||.|:||..:|||.|:.||
  Rat   543 PYKYPR-KVEFVSELPKTITGKIKRKELR 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	120/484 (25%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	116/477 (24%)
Acsm1	NP_001101972.2	AFD_class_I	46..573	CDD:302604	120/484 (25%)
Acsm1	NP_001101972.2	Acs	46..570	CDD:223442	118/482 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010