Protein Alignment CG6178 and Acsm2

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001171448.1
• Gene: Acsm2 / 233799
• MGIID: 2385289
• Length: 600
• Species: Mus musculus
• Alignment Length: 529
• Identity: 129/529 - (24%)
• Similarity: 219/529 - (41%)
• Gaps: 77/529 - (14%)

  Fly    48 VNG----VEYSASFMHKSIVRLAYILQ-KLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPL 107
            :||    :::|...:.::..:.|.:|. ..|:.:.|.|.:.......:.|.:...:..|....|.
Mouse    97 MNGSGKEIKWSFRELSEASKQTANVLSGACGLHRGDRVAVVLPRIPEWWLMILGCMRTGLVFMPG 161

  Fly   108 NVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKK--------FKNI 164
            .:.....::.:.:..||.:.|.|.......|..||....|:|..:.:|..|::        .|..
Mouse   162 TIQMRSSDILYRLQASKARAIVAGDEVAQEVDAVAPDCSFLKIKLLVSENSREGWLNFKALLKEA 226

  Fly   165 YDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKGVQLT--QMNLLATLD------ 221
            ..:.:.:|.|               ..:.:.|..:|||:|.||..:.:  .:.:.|.:|
Mouse   227 STIHQCVETE---------------SRESAAIYFTSGTSGPPKMAEHSHCSLGIKAKMDAASWTG 276

  Fly   222 ---SQIQPTVIPMEEVTLLTVI-----PWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAIEK 278
               |.|..|:  .:...::.::     ||         :..||:...|  ||||:.:..|..:..
Mouse   277 LSTSDIIWTI--SDTAWIMNILGAFLEPW---------VLGACIFVHL--LPKFDSQTVLKVLSS 328

  Fly   279 YRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSE 343
            |.:......|.:...|.:..: ..|....|.....|...|..||.:..|.:.|:. ||:.||.:|
Mouse   329 YPINTLVGAPIIYRMLLQQDL-SSYKFPHLHSCFSGGETLLPETLENWKAKTGLE-IREIYGQTE 391

  Fly   344 STLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGD-----GIMKGYIGD 403
            :.|...|......|||.:|........:||| :.|.:|...:.|::..:..     |:..||:.:
Mouse   392 TGLICRVSRTMKVKPGYLGTAFAHYDVQVID-EQGNVLPPGKEGDIAIRVKPIWPIGMFSGYVDN 455

  Fly   404 TKSTQTAIK-DGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAV 467
            .|.||..|: |.|| .||.|..|.:..|..:.|..::|...||::.|:|:|..|:.:..:.:.||
Mouse   456 PKKTQDNIRGDFWL-MGDRGIKDPEGYFHFIGRSDDIINSSGYRIGPSEVENALMEHPAVSETAV 519

  Fly   468 IGKPDEEAGELPLAFVV------KQANVQLTENEVIQ-FVNDNASPAKRLRGGVIFVDEIPKNPS 525
            |..||...||:..||||      .....|||  :|:| .|....:|.|..| .|.||.::||..:
Mouse   520 ISSPDPSRGEVVKAFVVLAPEFLSHDRDQLT--KVLQEHVKSVTAPYKYPR-KVEFVLDLPKTVT 581

  Fly   526 GKILRRILR 534
            |||.|..||
Mouse   582 GKIERAKLR 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	129/529 (24%)
Acsm2	NP_001171448.1	Adenylate forming domain, Class I superfamily	66..594	CDD:473059	129/529 (24%)