Protein Alignment CG6178 and sur-5

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_509229.1
• Gene: sur-5 / 180992
• WormBaseID: WBGene00006351
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 121/564 - (21%)
• Similarity: 213/564 - (37%)
• Gaps: 122/564 - (21%)

  Fly    52 EYSASFMHKSIVRLAYILQKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREV 116
            ||:...:.|.:.|:|..|:..|:...|.|.....|:.:..:|:||..||||.....:|.:....|
 Worm   156 EYTYDNLRKDVYRIATSLRNYGIGPGDTVCGFVPNTYDTLVAVFATAAVGAAWCSASVDFGPAGV 220

  Fly   117 DHAINLSKPKIIFA------SKITIDRVAKVASKNKFVKGI-----IALSGTSKKFKNIYDLKEL 170
            ........||::|.      .|..||:..|:   |:.||.:     |.:|.|....|  :|..:.
 Worm   221 LDRFRQVHPKVLFTVNHVTYKKKLIDQTDKI---NEIVKELPTLEKIVVSDTFTSVK--FDATKY 280

  Fly   171 MEDEKFKTQPDFTSPAAN----------KDEDVSLIVCSSGTTGLPKG-VQLTQMNLLATLDSQ- 223
            .:.:||.:..:|.:|.|:          ...|...::.||||||:||. |......||..::..
 Worm   281 NQSDKFSSLEEFKTPIADVVLPFVYTPVPFSDPLFVMFSSGTTGIPKAMVHTVGGTLLKHIEEHL 345

  Fly   224 IQPTVIPMEEVTLLTVIPW---------FHAFGCLTLI---------------------TTACVG 258
            :|......:.:...|...|         .::.|.:.|.                     |...:|
 Worm   346 VQGDSKKHDRMFFYTTCGWMMYNWMISFLYSKGSVVLFDECPLAPDTHIIMKIAAKTQSTMIGMG 410

  Fly   259 ARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETE 323
            |:|     ::|.|.|..                      |....||||.:..:....:||.:|..
 Worm   411 AKL-----YDEYLRLQI----------------------PFNTLYDLSKIHTVYSTGSPLKKECF 448

  Fly   324 DQIKERIG----VPFIRQGYGL------SESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTG 378
            ..|...|.    :..|..|..:      ...:||:        .||....|.:|:..|..:....
 Worm   449 AYINTYIAPGALIASISGGTDIIGCFVGGIKSLSI--------TPGECQCLFLGMDIKSFNYMDE 505

  Fly   379 KLLGANERGEL-CFKGDGIMKG-YIGDTKSTQ------TAIKDGWLHTGD---IGYYDDDFEFFI 432
            :::.::|:||| |......|.. ::.||...:      ..::..|.| ||   :.:.....|  :
 Worm   506 EIINSDEQGELVCVTPFPSMPSHFLNDTDGKKYRDAYFARLEPFWAH-GDFVRVNHSTGGVE--M 567

  Fly   433 VDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEA-GELPLAFVVKQANVQLTEN-- 494
            :.|....:...|.::..|||.:::.....|.|..|.|:..||. .|..|.||......:||.:
 Worm   568 LGRSDATLNRGGVRIGTAEIYSVVEKIPHIADCIVAGRLVEEGMDEEVLLFVKMVPGQELTHSIQ 632

  Fly   495 -EVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREML 537
             .::..:.::.|| :.:...:..||:||...|||.:...:::::
 Worm   633 AAIVSKLRNDMSP-RHVPNKIYAVDDIPYTSSGKKVEVAVKQIV 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	121/561 (22%)
sur-5	NP_509229.1	AACS	62..695	CDD:341265	121/564 (21%)