Protein Alignment CG6178 and acs-12

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_508035.1
• Gene: acs-12 / 180375
• WormBaseID: WBGene00009106
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 147/530 - (27%)
• Similarity: 255/530 - (48%)
• Gaps: 43/530 - (8%)

  Fly    25 RSLGQYILDKYKSFGDRTVLVD-------AVNGVEYSASFMHKSIVRLAYILQKLGVKQNDVVGL 82
            ::...::..:::.|.:...|:|       ....|...|.|:.||:|.|.       |::::||.|
 Worm    15 KTFHDFLFHEWEKFREDVALIDNDTFAQFTFQDVMQKADFIAKSLVYLK-------VEKSEVVLL 72

  Fly    83 SSE-NSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKI---TIDRVAKVAS 143
            ..: :.....:|:.|.:| ||.:..::......|:...:..|:.:.:|:..:   .||::.|..:
 Worm    73 VMDWSPAAIYIALGASMA-GAAIQVVSPKLQAWEMQFPVKESESRFVFSDPLGLHEIDKLMKTLN 136

  Fly   144 KNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKG 208
            :...:     :...|:.|.|.|   .::||..|..:.:...|....|.|:..:..|||..|..||
 Worm   137 REYRI-----ICTGSRDFANGY---PIIEDLAFAAKQNLPLPKIEPDTDIVYLPYSSGIHGKRKG 193

  Fly   209 VQLTQMNLLATLDSQIQPTVIPMEEV----TLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEE 269
            :..|...::|  .:.:........|.    |.||:||.....|...::.....|..:|....|..
 Worm   194 IVTTHKVMVA--KTMVMWNTSKHHEFRRGDTTLTMIPLHKQCGLDAILCALLNGLTVVTEKNFCV 256

  Fly   270 KLFLSAIEKYRVMMAFMVP---PLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERI- 330
            ..|::.|::|::....:.|   .||:|.|::   ..|::.||..::.||..::.|..::..|..
 Worm   257 HTFMTCIQRYKIRAVHLTPYLMNLMMFEAEN---HTYNIESLEWVVTGADAVTEELYEEFTEIFP 318

  Fly   331 GVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDG 395
            .|..:.|.||::|..|.....|..:..  |.|.|...:..||:|..|||.||..|:|::|.||..
 Worm   319 SVKTVTQTYGMTEVGLICRTYNKNYSP--SCGQLTANLEMKVLDILTGKELGPREKGQICVKGIA 381

  Fly   396 IMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTND 460
            ....|:.:.|:|:....|||..|||||::|::....:||::||:||..||||.|.|||.||||:.
 Worm   382 AESPYLNNPKATEEHFLDGWRRTGDIGFFDEEGNVHLVDKLKEMIKVFGYQVIPKEIETLLLTHQ 446

  Fly   461 KIKDAAVIGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPS 525
            .:::|||:...:|.:||.|:||||.:.....||:::..:||......|.| ..|.....:||:..
 Worm   447 AVEEAAVVAINNELSGERPVAFVVLKKGFVATEDDLKDYVNKRVIRYKHL-VRVNITQFLPKSAC 510

  Fly   526 GKILRRILRE 535
            |.:|||:|.|
 Worm   511 GTLLRRLLAE 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	147/530 (28%)
acs-12	NP_508035.1	Firefly_Luc_like	33..514	CDD:341237	141/504 (28%)