Protein Alignment CG6178 and acs-24

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_740831.1
• Gene: acs-24 / 171945
• WormBaseID: WBGene00016324
• Length: 461
• Species: Caenorhabditis elegans
• Alignment Length: 546
• Identity: 148/546 - (27%)
• Similarity: 242/546 - (44%)
• Gaps: 125/546 - (22%)

  Fly    25 RSLGQYILDKYKSFGDRTVLV--DAVNGVEYSASFMHKSIVRLAYILQKLGVKQNDV--VGLSSE 85
            |:.|:..|::...|.::|.|:  |.    |.|....|:.|.:...:|.:...|..:.  :.|...
 Worm     3 RNFGREFLEETSIFENKTCLIWRDR----EISFKEFHEYIGKWKNVLDEQKTKTTNPLRIALFCT 63

  Fly    86 NSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPK-IIFASKITIDRVAKVASKNKFVK 149
            ||.:....:.||...|.||.|||.:|...|:|..|:.|... ||.:..:.:|:
 Worm    64 NSPDILAIIVAGQLSGVTVIPLNPSYKKYEIDEYISKSIANFIIVSDDVDLDK------------ 116

  Fly   150 GIIALSGTSKKFKNIYDLKEL-MEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPKGVQLTQ 213
                           ::.:|: :..|.|.:....:|.|:..:....::..||||||.||..:.||
 Worm   117 ---------------FEEREVNLISELFTSNVTPSSTASTPENQGVIVFFSSGTTGPPKQFEYTQ 166

  Fly   214 MNLLATLDSQIQ-----PTVI-PMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLF 272
            ..|.:.:| ||:     |... |..:.....|:|:|||.|.:|:::....|..::...::.|..|
 Worm   167 RILCSQID-QIKAIRSDPRFFSPSTDDICYGVLPFFHAGGLITILSMIFSGCTVLINERWNEHEF 230

  Fly   273 LSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIR- 336
            |:..:.|:|.:.|:|||::.|.|.||:|..||||:|..:..|||....|...::.||:  |.:.
 Worm   231 LANCQNYKVSVLFLVPPVLNFFANHPLVSSYDLSALKTIYVGAAASPPENFAKVAERL--PELEN 293

  Fly   337 --QGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLG----------ANERGEL 389
              |.||.||  ..||:     |..|.             ...:||.:|          ..|..|:
 Worm   294 LIQLYGTSE--CGVLL-----CSTGK-------------GKASGKTVGWPFPFVELKINPENNEI 338

  Fly   390 CFKGDGIMKGYIGDTKSTQTAIKDGWLHTGDIGYYD-DDFEFFIVDRIKELIKYKGYQVPPAEIE 453
            ..|              :.||:::|::.|||:|... ...|..||.|.||::|.:|:||.|.|:|
 Worm   339 FVK--------------SATAMEEGFMETGDLGCLSFKTIELMIVGRSKEMMKIRGWQVNPNEVE 389

  Fly   454 ALLLTNDKIKDAAV-----------IGKPDEEAGELPLAFVVKQANVQLTENEVIQFVNDNASPA 507
            .::...:.:.|.||           ||.||.:|                   ::.:.|.||.:..
 Worm   390 DVIRKVEGVLDCAVYQNQEKLTAKIIGNPDSKA-------------------DIFKIVKDNLASY 435

  Fly   508 KRLRGGVIFVDEIPKNPSGKILRRIL 533
            |:| ..||||:|:|:|||||::|.:|
 Worm   436 KQL-DDVIFVEELPRNPSGKLVRHML 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	148/546 (27%)
acs-24	NP_740831.1	Adenylate forming domain, Class I superfamily	57..455	CDD:473059	132/481 (27%)