Protein Alignment CG6178 and LOC1277421

DIOPT Version :10

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_316885.6
• Gene: LOC1277421 / 1277421
• VectorBaseID: AGAMI1_002015
• Length: 602
• Species: Anopheles gambiae
• Alignment Length: 558
• Identity: 161/558 - (28%)
• Similarity: 268/558 - (48%)
• Gaps: 47/558 - (8%)

  Fly     7 PGNIVYGGPVTERQAQDSRSLGQYIL-----------DKYKSFGDRTVLVDAVNGVEYSASFMHK 60
            |...::.|..|......::||||.:|           .:....|.|||          :...|:.
Mosquito    65 PVTHIWTGLSTPPLFNTNQSLGQLVLGVLQRCDPAQVTQISDDGGRTV----------TCREMYL 119

  Fly    61 SIVRLAYILQKLGV-KQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSK 124
            ..||:|..|.:||. |...:..|:|.|..:.|...||..|:|..:..|:..::..:..|...:::
Mosquito   120 RTVRIAERLAQLGYGKHTPMAALASRNGEHVAPVAFACFALGIPINTLDTAFNVADFTHMFGVTR 184

  Fly   125 PKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANK 189
            |.::|.....::.|.:.|.:......|:.....:..::::.||.|....|......:...|..:
Mosquito   185 PALVFCESDILEVVREAAQRAAIAPEIVLFEERTAGYRHVLDLLEPTGTEDSFVPTNLDDPTTH- 248

  Fly   190 DEDVSLIVCSSGTTGLPKGVQLTQMNLLATLDSQIQPTVIPMEEVTLLTVIPWFHAFGCLTLITT 254
               |:.::||||||||.|||..|....:|.|.|..:  :.|.:.:...:.:.|...|..| :|.|
Mosquito   249 ---VAAVLCSSGTTGLSKGVTYTHTFCIANLPSLWR--MAPTDCLLAFSSLYWLSGFASL-IIGT 307

  Fly   255 ACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLS 319
            ....||::....|...|.|..::::.|.:||..|.....|...|::.:..|.:|.:.|||.|.:|
Mosquito   308 VSQAARVITRAPFTPTLALDMLQRHPVTIAFFSPFQSNLLVHEPLLAQTPLPALRLFLCGGARVS 372

  Fly   320 RETEDQIKE------RIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTG 378
            ::....::.      ||.:     |||:|||.|..|...:.: :...||.|:..:.|:::|....
Mosquito   373 KQLYAALQRCLPSHTRIQI-----GYGMSESCLVTLTDGNSY-RDDCVGTLQARVEARIVDDGLD 431

  Fly   379 KL-LGANERGELCFKGDGIMKGYIGDTKSTQTAIK-DGWLHTGDIGYYDDDFEFFIVDRIKELIK 441
            :. |..:|.||:..:......||.|:..:|...:. |||:.||||||:|.|...:::||.|::||
Mosquito   432 QCGLAPDEPGEIMLRVQIPFAGYYGNPDATAELMSPDGWIRTGDIGYFDRDGHLYVIDRKKDIIK 496

  Fly   442 YKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQ---ANVQLTENEVIQFVNDN 503
            |.|.|:.|.|:|.|......:.|..|:|.|| |..:||.|.|:::   ....||.::|.|||::.
Mosquito   497 YAGNQISPTELEVLAKQLTGVLDCCVVGVPD-EGTDLPAALVLREPGATGAALTADQVRQFVDER 560

  Fly   504 ASPAKRLRGGVIFVDEIPKNPSGKILRRILREMLKKQK 541
            .|..|.|||||.|.:|:|..|||||:||...|:::|.:
Mosquito   561 VSAHKHLRGGVYFTEEMPLTPSGKIVRRKCLEIVQKAR 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	Adenylate forming domain, Class I superfamily	9..536	CDD:473059	158/549 (29%)
LOC1277421	XP_316885.6	None