Protein Alignment CG6178 and ACSM2A

DIOPT Version :9

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001295101.1
• Gene: ACSM2A / 123876
• HGNCID: 32017
• Length: 577
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 131/498 - (26%)
• Similarity: 215/498 - (43%)
• Gaps: 53/498 - (10%)

  Fly    73 GVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDR 137
            |:::.|.|.:.......:.|.:...:..|....|..:.....::.:.:.:||.|.|.|....|..
Human   102 GLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQE 166

  Fly   138 VAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGT 202
            |..|||:...::  |.|..:.|......:.|:|:.:.........|.     .::.|.|..:|||
Human   167 VDTVASECPSLR--IKLLVSEKSCDGWLNFKKLLNEASTTHHCVETG-----SQEASAIYFTSGT 224

  Fly   203 TGLPKGVQ--LTQMNLLATLD--------SQIQPTVIPMEEVTLLTVI-----PWFHAFGCLTLI 252
            :||||..:  .:.:.|.|.:|        |.|..|:  .:...:|.::     ||  |.|
Human   225 SGLPKMAEHSYSSLGLKAKMDAGWTGLQASDIMWTI--SDTGWILNILCSLMEPW--ALG----- 280

  Fly   253 TTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAP 317
              ||....|  ||||:..:.|..:..|.: .:.|..|::..:.....:..|....|...:.....
Human   281 --ACTFVHL--LPKFDPLVILKTLSSYPI-KSMMGAPIVYRMLLQQDLSSYKFPHLQNCVTVGES 340

  Fly   318 LSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLG 382
            |..||.:..:.:.|:. ||:.||.:|:.|:.:|......|||.:|........::|| |.|.:|.
Human   341 LLPETLENWRAQTGLD-IRESYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQIID-DKGNVLP 403

  Fly   383 ANERGELCFKGD-----GIMKGYIGDTKSTQTAIK-DGWLHTGDIGYYDDDFEFFIVDRIKELIK 441
            ....|::..:..     ||..||:.:...|...|: |.|| .||.|..|:|..|..:.|..::|.
Human   404 PGTEGDIGIRVKPIRPIGIFSGYVDNPDKTAANIRGDFWL-LGDRGIKDEDGYFQFMGRANDIIN 467

  Fly   442 YKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQANV------QLTENEVIQFV 500
            ..||::.|:|:|..|:.:..:.:.|||..||...||:..||||..:..      |||: |:.|.|
Human   468 SSGYRIGPSEVENALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTK-ELQQHV 531

  Fly   501 NDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREMLKKQKSK 543
            ....:|.|..| .:.||..:||..:|||.|..||:...|...|
Human   532 KSVTAPYKYPR-KIEFVLNLPKTVTGKIQRAKLRDKEWKMSGK 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	129/490 (26%)
		Firefly_Luc_like	43..529	CDD:213279	125/482 (26%)
ACSM2A	NP_001295101.1	AFD_class_I	40..568	CDD:388389	129/491 (26%)
		Coenzyme A binding. /evidence=ECO:0000269|PubMed:19345228	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000269|PubMed:19345228	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920