Protein Alignment CG6178 and ACSM1

DIOPT Version :9

• Sequence 1: NP_651221.1
• Gene: CG6178 / 42867
• FlyBaseID: FBgn0039156
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001305819.1
• Gene: ACSM1 / 116285
• HGNCID: 18049
• Length: 577
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 139/552 - (25%)
• Similarity: 235/552 - (42%)
• Gaps: 106/552 - (19%)

  Fly    48 VNG----VEYSASFMHKSIVRLAYIL-QKLGVKQNDVVGLSSENSVNFALAMFAGLAVGATVAPL 107
            |||    |::|...|.....|:|.:. |..|::|.|.:.|.......:.|.....:..|....|.
Human    77 VNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCMRTGIIFIPA 141

  Fly   108 NVTYSDREVDHAINLSKPKIIFASKITIDRVA----KVASKNKFVKGIIALSGTSKKFKNIYDLK 168
            .:....:::.:.:.|||.|.|    :|||.:|    .:||:...:|..:.:|..|:  :...|.:
Human   142 TILLKAKDILYRLQLSKAKGI----VTIDALASEVDSIASQCPSLKTKLLVSDHSR--EGWLDFR 200

  Fly   169 ELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPK------GVQL-------TQMNLLATL 220
            .|::    ...|:.|. ..:|..|..:|..:|||||.||      |:.|       .::..|.|.
Human   201 SLVK----SASPEHTC-VKSKTLDPMVIFFTSGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTS 260

  Fly   221 D--------SQIQPTVIPMEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAIE 277
            |        ..|..|:..:.|       ||  ..||...|.         :||:|:.|:.:..:.
Human   261 DVSWCLSDSGWIVATIWTLVE-------PW--TAGCTVFIH---------HLPQFDTKVIIQTLL 307

  Fly   278 KYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMV-----LLCGAAPLSRETEDQIKERIGVPFIRQ 337
            ||.:...:.|..:      :.::.:.|.:|:..     ...|...:..:.:::.|.|.|: .:.:
Human   308 KYPINHFWGVSSI------YRMILQQDFTSIRFPALEHCYTGGEVVLPKDQEEWKRRTGL-LLYE 365

  Fly   338 GYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANERGE-------------- 388
            .||.||:.|..........|||.:|........:||| |.|.:|..|..|.
Human   366 NYGQSETGLICATYWGMKIKPGFMGKATPPYDVQVID-DKGSILPPNTEGNIGIRIKPVRPVSLF 429

  Fly   389 LCFKGDGIMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIE 453
            :|::||        ..|:.:....| :.:|||.|..|::.....:.|..::|...||::.|||:|
Human   430 MCYEGD--------PEKTAKVECGD-FYNTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVE 485

  Fly   454 ALLLTNDKIKDAAVIGKPDEEAGELPLAFVV------KQANVQLTENEVIQFVNDNASPAKRLRG 512
            :.|:.:..:.::||:|.||...||:..||:|      .....|||: |:.|.|....:|.|..|
Human   486 SALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTK-ELQQHVKSVTAPYKYPR- 548

  Fly   513 GVIFVDEIPKNPSGKILRRILREMLKKQKSKL 544
            .|.||.|:||..:|||.|:.||   ||:..::
Human   549 KVEFVSELPKTITGKIERKELR---KKETGQM 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	137/543 (25%)
		Firefly_Luc_like	43..529	CDD:213279	133/535 (25%)
ACSM1	NP_001305819.1	MACS_euk	45..574	CDD:341251	139/547 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920