DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6178 and acsf2

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_002939621.3	Gene:	acsf2 / 100497121	XenbaseID:	XB-GENE-993379	Length:	599	Species:	Xenopus tropicalis

Alignment Length:	574	Identity:	146/574 - (25%)
Similarity:	244/574 - (42%)	Gaps:	81/574 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PVTERQAQDSRSLGQYILDKYKSFGDRTVLVDAVNGVEYSASFMHKSIVRLAYILQKLGVKQNDV 79
            |:|      ||::.|.:|:......|:..::...:....:.|.:.|.:..||..|..||:|:.|.
Frog    56 PLT------SRTVHQCLLETTHRTPDQEAVIFPTSDTRKTFSQLIKDVDTLAAGLVALGLKRGDR 114

  Fly    80 VGLSSENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSK-PKIIFASKITIDRVAKVAS 143
            ||:...||..:.|..||....|..:..:|..|..||:::.:...: ..:||.|:....:..::.|
Frog   115 VGMWGPNSYEWILVQFATAQAGIILVSVNPAYQSRELEYVLRKVRCSALIFPSQFKSQKYYELLS 179

  Fly   144 -----------------KNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDE 191
                             |...:..::.|   .|:....:..:::||             |.|...
Frog   180 EVCPELETSPAGGLQCKKLPDLHTVVVL---DKRHPGTFLFQDVME-------------AGNPSS 228

  Fly   192 DVSL------IVC--------SSGTTGLPKGVQLTQMNLL--ATLDSQIQ--------PTVIPME 232
            .:.|      |.|        :|||||.|||..|:..|::  ::|..:..        .|.||
Frog   229 VLQLQDLQKQITCDDPINIQFTSGTTGSPKGATLSHHNIVNNSSLGGRRMGFNWRKGVRTAIP-- 291

  Fly   233 EVTLLTVIPWFHAFG-CLTLITTACVGARLVY-LPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLA 295
                   :|.:|..| .:..:..|..|..||: .|.::.:..|.||...:....:..|.:.:.|.
Frog   292 -------VPLYHCLGSVIGGMVMAVYGTTLVFPSPGYDPRALLEAISNEKCTCMYGTPTMYIDLL 349

  Fly   296 KHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLV--QNDEFC-K 357
            ..|....: :|:|...:...:....|...:|.....:..|..|||.:|::....:  .:|:|. |
Frog   350 SQPNFAAH-ISTLTTGVIAGSIAPPEVMKKILTETNMREIVIGYGTTENSPVTFMGFPHDDFTRK 413

  Fly   358 PGSVGVLKVGIYAKVIDPDTGKLLGANERGELCFKGDGIMKGYIGDTKSTQTAI-KDGWLHTGDI 421
            ..:||.:.....|||:|..||::...|..|||..:|..:|.||.||.:.|:..| .:.|..|||:
Frog   414 TETVGHVVSHTEAKVVDTTTGQIAPLNTPGELLIRGYCVMLGYWGDPERTKEVITPENWYRTGDV 478

  Fly   422 GYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVVKQ 486
            ...|:.....||.|.|::|...|..:.|||||..|.|:..:.:|.|||..||..||...|.:...
Frog   479 ATMDEYGYCRIVGRCKDMIIRGGENIYPAEIEDFLHTHPSVLEAQVIGVKDERMGEEVCACIRLY 543

  Fly   487 ANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILREMLKKQ 540
            .....|..|:.::.....|..|..| .::||:|.|...||||.:..|||.::|:
Frog   544 DGKTATPAEIKEYCKGKISHFKIPR-YIVFVNEYPLTVSGKIQKYKLRERMEKE 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	141/558 (25%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	134/533 (25%)
acsf2	XP_002939621.3	PRK08315	47..599	CDD:236236	146/574 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000