DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6178 and acsm3

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	XP_002932029.3	Gene:	acsm3 / 100491087	XenbaseID:	XB-GENE-486978	Length:	581	Species:	Xenopus tropicalis

Alignment Length:	514	Identity:	124/514 - (24%)
Similarity:	215/514 - (41%)	Gaps:	70/514 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 SIVRLAYILQKLGVKQNDVVGLSSENSV--------NFALAMFAGLAVGATVAPLNVTYSDREVD 117
            |...|.::.:|.....:|...|...:.|        .:.|...|.:..|..:.|.....:.:::.
Frog    91 SFEELGFLSRKAANVLSDACNLKPGDRVIVILPRVPEWWLLNVACIRAGVVLIPGTTQLTAKDIL 155

  Fly   118 HAINLSKPKIIFASKITIDRVAKVASKNKFVKGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDF 182
            |.:..|..|.|..|...::.|..||:::.|::..:.:|  :::.....|.|.|     |:...|.
Frog   156 HRLQTSMAKCIITSDCLVEAVDSVAAQSPFLQTKMLIS--TERRDGWLDFKGL-----FQVANDK 213

  Fly   183 TSPAANKDEDVSLIVCSSGTTGLPK---------GVQLTQMNLLATLDSQIQPTVIP-------- 230
            .:....|..|...|..:|||||.||         |:.| ::|....:|  :.||.|.
Frog   214 HTCVKTKSSDPMTIFFTSGTTGSPKMTEHSHCSYGLGL-KVNGKYWMD--LTPTDIVWNMSDTGW 275

  Fly   231 MEEVTLLTVIPWFHAFGCLTLITTACVGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLA 295
            .:........||         |..:||.|.  .:|:|:..:.|..:..:.:......|.....|.
Frog   276 AKSAWSSVFAPW---------IQGSCVFAH--SMPRFDTNIVLKTLSTFPITTFCSAPTAYRMLV 329

  Fly   296 KHPIVDKYDLSSLMVLLCGAAPLSRETEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGS 360
            ..... .|...||...:....|::.:..:|.||:.|:. |.:|||.:|:.|..........||||
Frog   330 LQNFA-SYKFKSLQHCVSAGEPINPQVMEQWKEQTGLD-IYEGYGQTETVLICGTFKGMKIKPGS 392

  Fly   361 VGVLKVGIYAKVIDPDTGKLLGANERGELCF-----KGDGIMKGYIGDTKSTQTAIKDGWLHTGD 420
            :|........:::| :.|.:|...:.|::..     |...:...|.||.:.|.:..:..:..|||
Frog   393 MGKPSPAYDVEIVD-ENGNVLPQGKEGDIAIRILPQKPFCLFSQYTGDPERTASTRRGNFYLTGD 456

  Fly   421 IGYYDDDFEFFIVDRIKELIKYKGYQVPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVV- 484
            .|..|:|..|:.|.|..::|...||::.|.|:|:.|:.:..:.::||:..||...||:..||||
Frog   457 RGIKDEDGYFWFVGRSDDVILSSGYRIGPFEVESALIEHPAVAESAVVSSPDPIRGEVVKAFVVL 521

  Fly   485 ---------KQANVQLTENEVIQFVNDNASPAKRLRGGVIFVDEIPKNPSGKILRRILR 534
                     ::..::|.|:     |.:..:|.|..| .:.||.::||..||||.|..||
Frog   522 APAYNGYDPEKLALELQEH-----VRNITAPYKYPR-KIEFVQQLPKTVSGKIRRNELR 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	124/514 (24%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	120/507 (24%)
acsm3	XP_002932029.3	MACS_euk	49..578	CDD:341251	124/514 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920