DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6178 and acsm3

DIOPT Version :9

Sequence 1:	NP_651221.1	Gene:	CG6178 / 42867	FlyBaseID:	FBgn0039156	Length:	544	Species:	Drosophila melanogaster
Sequence 2:	NP_001104706.1	Gene:	acsm3 / 100002035	ZFINID:	ZDB-GENE-080220-22	Length:	591	Species:	Danio rerio

Alignment Length:	555	Identity:	140/555 - (25%)
Similarity:	233/555 - (41%)	Gaps:	81/555 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 ILDKYKS---FGDRTVLVDA--VN--GVEYSASF----MHKSIVRLAYILQKL-GVKQNDVVGLS 83
            :|:|:::   .|.|:.|...  ||  |.|...||    .|..  :||.:|::: .:::.|.|.|.
Zfish    67 VLEKWETKEKSGQRSSLPALWWVNDHGTEVRWSFEELGFHSR--KLANVLRQVCSLERGDRVFLI 129

  Fly    84 SENSVNFALAMFAGLAVGATVAPLNVTYSDREVDHAINLSKPKIIFASKITIDRVAKVASKNKFV 148
            ......:.|...|.:..|..:.|.....:.|::.|.:..|..|.:...:.....:..||.....:
Zfish   130 LPRVPEWWLVNVACIRTGTVLIPGTSQLTARDMRHRLITSGAKCVITDETLAPLLDTVALDCPSI 194

  Fly   149 KGIIALSGTSKKFKNIYDLKELMEDEKFKTQPDFTSPAANKDEDVSLIVCSSGTTGLPK------ 207
            ...:.||  .|......:|.|||.    :...|......:.:|.:: |..:|||||.||
Zfish   195 STKLLLS--HKPMDGWGNLTELMG----RVSDDHVCVDTSSEEPMT-IFFTSGTTGSPKMTQHSH 252

  Fly   208 ---GVQLTQMNLLATLDSQIQPTVIPMEEVTLLT-------------VIPWFHAFGCLTLITTAC 256
               |:.|| :|....||       :..::|...|             ..||         |..||
Zfish   253 CSYGLGLT-VNGRYWLD-------LTEQDVFWNTSDTGWAKSAWSSVFAPW---------IQGAC 300

  Fly   257 VGARLVYLPKFEEKLFLSAIEKYRVMMAFMVPPLMVFLAKHPIVDKYDLSSLMVLLCGAAPLSRE 321
            |...  ::|:|:....|..:..|.: ..|...|....:.....:.||...:|...||...|::.|
Zfish   301 VFVH--HMPRFDTNTVLKTLSHYPI-TTFCTAPTAYRMLVQDDLSKYKFQALEHCLCAGEPINPE 362

  Fly   322 TEDQIKERIGVPFIRQGYGLSESTLSVLVQNDEFCKPGSVGVLKVGIYAKVIDPDTGKLLGANER 386
            ...:.||..|:. |.:|||.:|:.|..........||||.|....|...:|:| :.|.::...:.
Zfish   363 VMCKWKELTGLD-IYEGYGQTETVLIAGTFKGMKIKPGSFGKASPGYDVQVVD-ENGSVVPKGQE 425

  Fly   387 GELCFKGD-----GIMKGYIGDTKSTQTAIKDGWLHTGDIGYYDDDFEFFIVDRIKELIKYKGYQ 446
            |:|..:..     .:...|.|:...|....:..:..|||.|..||:...:.:.|..::|...||:
Zfish   426 GDLGIRVKPERPFSLFTEYTGEPVRTAECFRGDFYLTGDRGMMDDEGYLWFIGRSDDVILSAGYR 490

  Fly   447 VPPAEIEALLLTNDKIKDAAVIGKPDEEAGELPLAFVV------KQANVQLTENEVIQFVNDNAS 505
            :.|.|:|..|:.:..:.::||:..||...||:..||||      .:|:.:|.: |:...|....:
Zfish   491 IGPFEVENALIEHPAVAESAVVSSPDPVRGEVVKAFVVLTADFKSRAHKELIK-ELQTHVKSITA 554

  Fly   506 PAKRLRGGVIFVDEIPKNPSGKILRRILREMLKKQ 540
            |.|..| .:.|||::||..|||| ||:  |:.||:
Zfish   555 PYKYPR-KIEFVDQLPKTVSGKI-RRV--ELRKKE 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6178	NP_651221.1	PLN02246	26..537	CDD:215137	138/550 (25%)
CG6178	NP_651221.1	Firefly_Luc_like	43..529	CDD:213279	130/527 (25%)
acsm3	NP_001104706.1	Acs	54..583	CDD:223442	138/551 (25%)
acsm3	NP_001104706.1	AFD_class_I	57..586	CDD:302604	140/555 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010