Protein Alignment p38a and CDK11B

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_011540792.1
• Gene: CDK11B / 984
• HGNCID: 1729
• Length: 804
• Species: Homo sapiens
• Alignment Length: 366
• Identity: 112/366 - (30%)
• Similarity: 175/366 - (47%)
• Gaps: 61/366 - (16%)

  Fly    25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD 89
            :|.|..:..|.||.|.:|..:.|:..||:|:|....:.......:.||:..:....|.|::.:.:
Human   447 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVRE 511

  Fly    90 IFHPHPANGSLENFQQVYLVTHLMDADLNNIIR--MQHLSDDHVQFLVYQILRGLKYIHSAGVIH 152
            |     ..||  |..::|:|.:.::.||.:::.  .|......|:.|:.|:|||:|::|...::|
Human   512 I-----VVGS--NMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH 569

  Fly   153 RDLKPSNIAVNEDCELRILDFGLARPTENEMTGY---VATRWYRAPEIMLNWMHYDQTVDIWSVG 214
            ||||.||:.::....|::.||||||...:.:..|   |.|.||||||::|....|...||:||||
Human   570 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVG 634

  Fly   215 CIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSF----- 274
            ||..||:|::.||||...|.|:|.:.:.||||         ||........||.:|..:|
Human   635 CIFGELLTQKPLFPGKSEIDQINKVFKDLGTP---------SEKIWPGYSELPAVKKMTFSEHPY 690

  Fly   275 KNVFKNANPL----AIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFEDMD 335
            .|:.|....|    ..||:.|.|.....:||:||:.|.|.|                   |.:..
Human   691 NNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEY-------------------FRETP 736

  Fly   336 LPVD---------KWKELIYKEVTNFKPPP---SYAQVLKD 364
            ||:|         |.::...|..|:.:||.   .|:|:..|
Human   737 LPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDD 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	107/351 (30%)
CDK11B	XP_011540792.1	STKc_CDC2L1	441..732	CDD:173741	100/319 (31%)