Protein Alignment p38a and CDKL1

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_004187.3
• Gene: CDKL1 / 8814
• HGNCID: 1781
• Length: 357
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 99/299 - (33%)
• Similarity: 156/299 - (52%)
• Gaps: 16/299 - (5%)

  Fly    25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD 89
            |:.:..:|.|:||.|.|...|.|...|||||........|..|...||:|:||.:.|.|::.||:
Human     4 YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLLE 68

  Fly    90 IFHPHPANGSLENFQQVYLVTHLMD-ADLNNIIRMQHLSDDH-VQFLVYQILRGLKYIHSAGVIH 152
            :|         ...::::||....| ..|:.:.|.|....:| |:.:.:|.|:.:.:.|....||
Human    69 VF---------RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKHNCIH 124

  Fly   153 RDLKPSNIAVNEDCELRILDFGLAR----PTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSV 213
            ||:||.||.:.:...:::.|||.||    |:: ..|.||||||||:||:::....|...||:|::
Human   125 RDVKPENILITKHSVIKLCDFGFARLLTGPSD-YYTDYVATRWYRSPELLVGDTQYGPPVDVWAI 188

  Fly   214 GCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF 278
            ||:.|||::...|:||...:.||.||.:.||.......:..|:....|.::...|......:..|
Human   189 GCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPEDMEPLELKF 253

  Fly   279 KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAE 317
            .|.:..|:.||:..|.:|..:|:|.|:.|.|||.|...|
Human   254 PNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIRE 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	99/299 (33%)
CDKL1	NP_004187.3	STKc_CDKL1_4	2..287	CDD:270837	96/292 (33%)
		[NKR]KIAxRE	45..51		1/5 (20%)