DRSC/TRiP Functional Genomics Resources

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Protein Alignment p38a and SMK1

DIOPT Version :9

Sequence 1:NP_001163711.1 Gene:p38a / 42866 FlyBaseID:FBgn0015765 Length:366 Species:Drosophila melanogaster
Sequence 2:NP_015379.1 Gene:SMK1 / 856167 SGDID:S000006258 Length:388 Species:Saccharomyces cerevisiae


Alignment Length:354 Identity:133/354 - (37%)
Similarity:202/354 - (57%) Gaps:28/354 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 IPDIYQDLQPVGSGAYGQVSKAVVRGTN--MHVAIKKLARPFQSAVHAKRTYRELRLLKHM-DHE 82
            ||..|:.:|.:|.||||.|.....:|.:  ..:|:||::..|...:..||..|||:.:... .|:
Yeast    34 IPGYYEIIQFLGKGAYGTVCSVKFKGRSPAARIAVKKISNIFNKEILLKRAIRELKFMNFFKGHK 98

  Fly    83 NVIGLLD--IFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQ-HLSDDHVQFLVYQILRGLKY 144
            |::.|:|  |....|.:|       :|....|:|.||..:|... .||:.|:::.:||||.||||
Yeast    99 NIVNLIDLEIVTSSPYDG-------LYCYQELIDYDLAKVIHSSVQLSEFHIKYFLYQILCGLKY 156

  Fly   145 IHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----------PTENEMTGYVATRWYRAPEIM 198
            ||||.||||||||.||....:..|:|.||||||           ..:..:|.|||||||||||::
Yeast   157 IHSADVIHRDLKPGNILCTLNGCLKICDFGLARGIHAGFFKCHSTVQPHITNYVATRWYRAPELL 221

  Fly   199 LNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYI 263
            |:...|.::||||:||||:||...|:.:|.|.|.:||:..|:::||||..:.|.|..:..|.:..
Yeast   222 LSNQPYSKSVDIWAVGCILAEFYARKPVFMGRDSMHQIFEIIKVLGTPDKDILIKFGTIKAWNLG 286

  Fly   264 QSL--PPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQT--S 324
            ::.  |..|...:.|:|..|:..||:|:|.:|..|:..|:..|:|:|||:|.:..:|..|..  .
Yeast   287 KNSNNPVYKKIPWSNIFPFASHEAINLIESLLHWDSTHRLNVEQAISHPFLNEVRKPDDEPVCLQ 351

  Fly   325 PPYDHSFEDMDLPVDKWKELIYKEVTNFK 353
            .|:|.::|.....:.|.::.:.:||.|||
Yeast   352 GPFDFTYESELNSMSKLRDYLVEEVKNFK 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
p38aNP_001163711.1 STKc_p38 9..354 CDD:143356 133/354 (38%)
S_TKc 25..312 CDD:214567 119/305 (39%)
SMK1NP_015379.1 PKc_like 37..376 CDD:419665 126/345 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0660
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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