DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38a and zgc:171775

DIOPT Version :9

Sequence 1:	NP_001163711.1	Gene:	p38a / 42866	FlyBaseID:	FBgn0015765	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001104637.1	Gene:	zgc:171775 / 562552	ZFINID:	ZDB-GENE-030131-4309	Length:	359	Species:	Danio rerio

Alignment Length:	354	Identity:	200/354 - (56%)
Similarity:	260/354 - (73%)	Gaps:	3/354 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVH 65
            |:..:...|::|||.:|.|::||.|..|:||||||||.|..||.:.|...||||||.|||||.:|
Zfish     1 MASPLKTGFHRLDIQKTTWDVPDRYTSLKPVGSGAYGTVCFAVDQKTKEKVAIKKLYRPFQSLIH 65

  Fly    66 AKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDH 130
            |||.|||||||:|:.|:|||.||::|.|   :.|||.|...|:|...:..||.:|::.:.|:.:.
Zfish    66 AKRAYRELRLLRHIQHDNVICLLNVFTP---DSSLEKFDTFYMVMPFVAQDLGHIMKRKQLTSNV 127

  Fly   131 VQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAP 195
            :.:|.||||||||||||||:|||||||:|:||:|:|||:||||||||.||.||||||.|||||||
Zfish   128 ITYLFYQILRGLKYIHSAGIIHRDLKPNNLAVDENCELKILDFGLARHTETEMTGYVVTRWYRAP 192

  Fly   196 EIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESAR 260
            |::.|||||.||||:|:.|||:||:||...||||:|.|.||..|:.:.|||.:..:.|:.|:.|:
Zfish   193 EVIFNWMHYTQTVDVWTAGCILAEMITGEVLFPGSDSIDQLKKILNLTGTPNSTLVLKMQSKDAQ 257

  Fly   261 SYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSP 325
            ||::|||..|.::||.||...:|.||||||.||.||.|.|::|:..||||||.::.:|..|..||
Zfish   258 SYVRSLPVQKKKAFKEVFSGMDPNAIDLLEGMLVLDPEVRLSAKNGLSHPYLSEFHDPENEPVSP 322

  Fly   326 PYDHSFEDMDLPVDKWKELIYKEVTNFKP 354
            |||.|||.|||.|.:||.||:.|:..|.|
Zfish   323 PYDDSFESMDLAVSEWKSLIHMEIMTFDP 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	198/344 (58%)
p38a	NP_001163711.1	S_TKc	25..312	CDD:214567	168/286 (59%)
zgc:171775	NP_001104637.1	STKc_p38	9..351	CDD:143356	198/344 (58%)
zgc:171775	NP_001104637.1	S_TKc	25..309	CDD:214567	168/286 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.880