Protein Alignment p38a and MAPK13

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_002745.1
• Gene: MAPK13 / 5603
• HGNCID: 6875
• Length: 365
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 205/355 - (57%)
• Similarity: 261/355 - (73%)
• Gaps: 5/355 - (1%)

  Fly     1 MSVSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVH 65
            ||:...|.|||.|:|:|.||:|..|.....|||||||.|..|:.:.:...||||||:|||||.:.
Human     1 MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIF 65

  Fly    66 AKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDH 130
            |||.||||.|||||.|||||||||:|.|   ..||.||...|||...|..||..|:.|: .|::.
Human    66 AKRAYRELLLLKHMQHENVIGLLDVFTP---ASSLRNFYDFYLVMPFMQTDLQKIMGME-FSEEK 126

  Fly   131 VQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAP 195
            :|:||||:|:||||||||||:||||||.|:||||||||:||||||||..:.||||||.|||||||
Human   127 IQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMTGYVVTRWYRAP 191

  Fly   196 EIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESAR 260
            |::|:||||:||||||||||||||::|.:|||.|.|::.||..|:::.|.|..||::|::.::|:
Human   192 EVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKLNDKAAK 256

  Fly   261 SYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVE-QTS 324
            |||||||....:.|..:|..|:|.|.||||||||||.:||:||.:||:||:.|.:.:|..| :..
Human   257 SYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAAQALTHPFFEPFRDPEEETEAQ 321

  Fly   325 PPYDHSFEDMDLPVDKWKELIYKEVTNFKP 354
            .|:|.|.|...|.||:||:.||||:.||.|
Human   322 QPFDDSLEHEKLTVDEWKQHIYKEIVNFSP 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	201/345 (58%)
MAPK13	NP_002745.1	STKc_p38delta	9..351	CDD:143384	201/345 (58%)
		TXY	180..182		1/1 (100%)