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Protein Alignment p38a and MAPK11

DIOPT Version :9

Sequence 1:	NP_001163711.1	Gene:	p38a / 42866	FlyBaseID:	FBgn0015765	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_002742.3	Gene:	MAPK11 / 5600	HGNCID:	6873	Length:	364	Species:	Homo sapiens

Alignment Length:	347	Identity:	227/347 - (65%)
Similarity:	277/347 - (79%)	Gaps:	3/347 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYREL 73
            ||:.::|:|.||:|...|.|:||||||||.|..|........||:|||:|||||.:||:||||||
Human     8 FYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQSLIHARRTYREL 72

  Fly    74 RLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQI 138
            |||||:.|||||||||:|.|..   |:|:|.:|||||.||.||||||::.|.|||:||||||||:
Human    73 RLLKHLKHENVIGLLDVFTPAT---SIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQL 134

  Fly   139 LRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMH 203
            |||||||||||:|||||||||:|||||||||||||||||..:.||||||||||||||||||||||
Human   135 LRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWMH 199

  Fly   204 YDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPP 268
            |:|||||||||||||||:..:.||||:|:|.||..|||::|||..|.|.|||||.||:|||||||
Human   200 YNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPP 264

  Fly   269 MKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSFED 333
            |..:...::|:.|||||||||.:||.||:::|::|.|||:|.|..:|.:|..|..:.|||.|.|.
Human   265 MPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEA 329

  Fly   334 MDLPVDKWKELIYKEVTNFKPP 355
            .:..:::||||.|:||.:||||
Human   330 KERTLEEWKELTYQEVLSFKPP 351

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.