Protein Alignment p38a and MAPK7

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_006721620.1
• Gene: MAPK7 / 5598
• HGNCID: 6880
• Length: 822
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 163/349 - (46%)
• Similarity: 230/349 - (65%)
• Gaps: 18/349 - (5%)

  Fly    19 WEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHEN 83
            :::.|.|:.::.:|:||||.||.|..|.|...|||||:...|....:||||.|||::|||..|:|
Human    49 FDVGDEYEIIETIGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDN 113

  Fly    84 VIGLLDIFHPHPANGSLENFQQV------YLVTHLMDADLNNIIR-MQHLSDDHVQFLVYQILRG 141
            :|.:.||..|....|   .|:.|      |:|..||::||:.||. .|.|:.:||::.:||:|||
Human   114 IIAIKDILRPTVPYG---EFKSVPYGVPGYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRG 175

  Fly   142 LKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLAR-----PTENE--MTGYVATRWYRAPEIML 199
            |||:|||.||||||||||:.|||:|||:|.|||:||     |.|::  ||.|||||||||||:||
Human   176 LKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELML 240

  Fly   200 NWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQ 264
            :...|.|.:|:||||||..|::.||.||||.:::|||.|||.:||||....::.:.:|..|:|||
Human   241 SLHEYTQAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQ 305

  Fly   265 SLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVE-QTSPPYD 328
            ||||.:...::.|:..|:..|:.||.:||..:...||:|..||.||:|.||.:|..| ..:||:|
Human   306 SLPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCAPPFD 370

  Fly   329 HSFEDMDLPVDKWKELIYKEVTNF 352
            .:|:...|..::.||.|..|:.:|
Human   371 FAFDREALTRERIKEAIVAEIEDF 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	163/349 (47%)
MAPK7	XP_006721620.1	STKc_ERK5	49..390	CDD:270842	161/343 (47%)