Protein Alignment p38a and MAPK3

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_002737.2
• Gene: MAPK3 / 5595
• HGNCID: 6877
• Length: 379
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 161/337 - (47%)
• Similarity: 226/337 - (67%)
• Gaps: 12/337 - (3%)

  Fly    25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD 89
            |..||.:|.||||.||.|........|||||:: ||:...:.:||.||:::|....||||||:.|
Human    42 YTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKIS-PFEHQTYCQRTLREIQILLRFRHENVIGIRD 105

  Fly    90 IFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRD 154
            |...    .:||..:.||:|..||:.||..:::.|.||:||:.:.:|||||||||||||.|:|||
Human   106 ILRA----STLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRD 166

  Fly   155 LKPSNIAVNEDCELRILDFGLARPTENE------MTGYVATRWYRAPEIMLNWMHYDQTVDIWSV 213
            |||||:.:|..|:|:|.||||||..:.|      :|.|||||||||||||||...|.:::|||||
Human   167 LKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSV 231

  Fly   214 GCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVF 278
            |||:||:::.|.:|||..::.|||.|:.:||:|..|.|..|.:..||:|:||||.....::..:|
Human   232 GCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLF 296

  Fly   279 KNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTS-PPYDHSFEDMDLPVDKWK 342
            ..::..|:|||::||..:..||||.||||:|||||:|.:|:.|..: .|:..:.|..|||.::.|
Human   297 PKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFAMELDDLPKERLK 361

  Fly   343 ELIYKEVTNFKP 354
            |||::|...|:|
Human   362 ELIFQETARFQP 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	160/335 (48%)
MAPK3	NP_002737.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_ERK1_2_like	36..370	CDD:270839	159/332 (48%)
		TXY	202..204		1/1 (100%)