Protein Alignment p38a and mapk12

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_001017080.1
• Gene: mapk12 / 549834
• XenbaseID: XB-GENE-485782
• Length: 363
• Species: Xenopus tropicalis
• Alignment Length: 356
• Identity: 214/356 - (60%)
• Similarity: 277/356 - (77%)
• Gaps: 5/356 - (1%)

  Fly     1 MSVS-ITKK-FYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSA 63
            ||.| :.|| :|:.|:|:|.||:.:.|:||..|||||||.|..::...|...||||||.|||||.
 Frog     1 MSTSPLPKKGYYRQDVNKTVWEVKERYRDLVAVGSGAYGTVCSSLDTRTGTKVAIKKLYRPFQSE 65

  Fly    64 VHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSD 128
            :.|||.||||||||||.|||||||||:|.|   :.:||||...|||...|..||..|::.:.||:
 Frog    66 LFAKRAYRELRLLKHMQHENVIGLLDVFTP---DSTLENFNDFYLVMPFMGTDLGKIMKHEKLSE 127

  Fly   129 DHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYR 193
            |.:||||||||||||||||||:|||||||.|:||||||||:||||||||.|::||||||.|||||
 Frog   128 DRIQFLVYQILRGLKYIHSAGIIHRDLKPGNLAVNEDCELKILDFGLARHTDSEMTGYVVTRWYR 192

  Fly   194 APEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSES 258
            |||::||||||.||||||||||||||:.|.|.||.|.||:.||..||::.|||..:|::|:.|..
 Frog   193 APEVILNWMHYTQTVDIWSVGCIMAEMYTGRPLFKGNDHLDQLTEIMKITGTPTQDFVQKLQSPD 257

  Fly   259 ARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQT 323
            |::||:|||.::.:.|.::.:.|||||:::|||||.|||||||||.|||:|||.|::.:...|..
 Frog   258 AKNYIKSLPKVQKKDFGSLLRYANPLAVNILEKMLVLDAEKRITATEALAHPYFEQFHDIDDETE 322

  Fly   324 SPPYDHSFEDMDLPVDKWKELIYKEVTNFKP 354
            :.|||.||::::||:::|:.|.:||:|::||
 Frog   323 AEPYDDSFDNVNLPLEEWRRLTHKELTSYKP 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	207/344 (60%)
mapk12	NP_001017080.1	STKc_p38gamma	11..353	CDD:143385	207/344 (60%)