DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38a and SRPK

DIOPT Version :9

Sequence 1:	NP_001163711.1	Gene:	p38a / 42866	FlyBaseID:	FBgn0015765	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001369087.1	Gene:	SRPK / 36706	FlyBaseID:	FBgn0286813	Length:	1009	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	52/173 - (30%)
Similarity:	81/173 - (46%)	Gaps:	30/173 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 EDC--ELRILDFGLARPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTL 226
            ::|  .::|.|.|.|...:...|..:.||.||:.|:::. ..|:.:.||||..|::.||.|...|
  Fly   597 DECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIG-AGYNTSADIWSTACMVFELATGDYL 660

  Fly   227 FP---------GTDHIHQLNLIMEMLGTPPAEFLKKISSESARSY-----IQSLPPMKGRSFKNV 277
            |.         ..||:..   |:|:||..|.|.|.. .:.:|:|:     ::::..:|.....:|
  Fly   661 FEPHSGESYTRDEDHLAH---IIELLGPIPREILLN-GTYAAKSFTRSCELRNISGLKPWGLMDV 721

  Fly   278 F--------KNANPLAIDLLEKMLELDAEKRITAEEALSHPYL 312
            .        |:|...| ..|..|||.|..||.||.|.|.||:|
  Fly   722 LLEKYEWSQKDAASFA-SFLTPMLEFDPNKRATAAECLQHPWL 763

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	52/173 (30%)
p38a	NP_001163711.1	S_TKc	25..312	CDD:214567	51/171 (30%)
SRPK	NP_001369087.1	PKc_like	159..>318	CDD:419665
SRPK	NP_001369087.1	PKc_like	<600..763	CDD:419665	50/168 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24055
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100