Protein Alignment p38a and Mapk10

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_001394501.1
• Gene: Mapk10 / 26414
• MGIID: 1346863
• Length: 494
• Species: Mus musculus
• Alignment Length: 389
• Identity: 178/389 - (45%)
• Similarity: 252/389 - (64%)
• Gaps: 34/389 - (8%)

  Fly     1 MSVS-ITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAV 64
            ||.| :..:||.:::..:.:.:...||:|:|:||||.|.|..|.....:.:||||||:||||:..
Mouse    69 MSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQT 133

  Fly    65 HAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDD 129
            ||||.||||.|:|.::|:|:|.||::|.|..   :||.||.||||..||||:|..:|:|: |..:
Mouse   134 HAKRAYRELVLMKCVNHKNIISLLNVFTPQK---TLEEFQDVYLVMELMDANLCQVIQME-LDHE 194

  Fly   130 HVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARP--TENEMTGYVATRWY 192
            .:.:|:||:|.|:|::||||:||||||||||.|..||.|:||||||||.  |...||.||.||:|
Mouse   195 RMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYY 259

  Fly   193 RAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSE 257
            ||||::|. |.|.:.||||||||||.|::..:.||||.|:|.|.|.::|.||||..||:||: ..
Mouse   260 RAPEVILG-MGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKL-QP 322

  Fly   258 SARSYIQSLPPMKGRSFKNVFKNA--------NPL----AIDLLEKMLELDAEKRITAEEALSHP 310
            :.|:|:::.|...|.:|..:|.::        |.|    |.|||.|||.:|..|||:.::||.||
Mouse   323 TVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHP 387

  Fly   311 YLEKYAEPSVEQTSPP--YDHSFEDMDLPVDKWKELIYKEVTNF-----------KPPPSYAQV 361
            |:..:.:|:..:..||  ||...::.:..:::|||||||||.|.           :|.||.|.|
Mouse   388 YINVWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAAV 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	170/371 (46%)
Mapk10	NP_001394501.1	STKc_JNK	93..428	CDD:270840	165/340 (49%)