Protein Alignment p38a and jnk-1

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_001021270.1
• Gene: jnk-1 / 177460
• WormBaseID: WBGene00002178
• Length: 463
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 164/373 - (43%)
• Similarity: 237/373 - (63%)
• Gaps: 35/373 - (9%)

  Fly     2 SVSITKKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHA 66
            |:.:.:.:|.:.|...:..:...||:|:.:||||.|.|..|.....|..||||||:||||:..||
 Worm    96 SIHVPENYYSVTIGEAQMVVLKRYQNLRLIGSGAQGIVCSAFDTVRNEQVAIKKLSRPFQNVTHA 160

  Fly    67 KRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHV 131
            ||.||||:|:..::|:|:||:|:.|.|..   .|:.|..:|:|..||||:|..:|:|. |..:.:
 Worm   161 KRAYRELKLMSLVNHKNIIGILNCFTPQK---KLDEFNDLYIVMELMDANLCQVIQMD-LDHERL 221

  Fly   132 QFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENE---MTGYVATRWYR 193
            .:|:||:|.|::::||||:||||||||||.|..||.|:|||||||| |..|   ||.||.||:||
 Worm   222 SYLLYQMLCGIRHLHSAGIIHRDLKPSNIVVRSDCTLKILDFGLAR-TAIEAFMMTPYVVTRYYR 285

  Fly   194 APEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSES 258
            |||::|. |.|.:.||:||:|||..|||..|.||||.|||.|...|:|.||||...||::: ..:
 Worm   286 APEVILG-MGYKENVDVWSIGCIFGELIRGRVLFPGGDHIDQWTRIIEQLGTPDRSFLERL-QPT 348

  Fly   259 ARSYIQSLPPMKGRSFKNVFK-NANPL-----------AIDLLEKMLELDAEKRITAEEALSHPY 311
            .|:|:::.|..:...|:.:|. |..|:           |.|||.:||.:|.|:||:.::||.|||
 Worm   349 VRNYVENRPRYQATPFEVLFSDNMFPMTADSSRLTGAQARDLLSRMLVIDPERRISVDDALRHPY 413

  Fly   312 -------LEKYAEPSVEQTSPPYDHSFEDMDLPVDKWKELIYKEVTNF 352
                   :|.||.|.:     ||||:. |::..||.|:|.|::|:|::
 Worm   414 VNVWFDEIEVYAPPPL-----PYDHNM-DVEQNVDSWREHIFRELTDY 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	163/366 (45%)
jnk-1	NP_001021270.1	STKc_JNK	118..452	CDD:270840	159/346 (46%)