Protein Alignment p38a and MAPK14

DIOPT Version :9

• Sequence 1: NP_001163711.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_011512612.2
• Gene: MAPK14 / 1432
• HGNCID: 6876
• Length: 401
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 226/310 - (72%)
• Similarity: 258/310 - (83%)
• Gaps: 3/310 - (0%)

  Fly    47 TNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTH 111
            |.:.||:|||:|||||.:|||||||||||||||.|||||||||:|.|   ..|||.|..||||||
Human    87 TGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTP---ARSLEEFNDVYLVTH 148

  Fly   112 LMDADLNNIIRMQHLSDDHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLA 176
            ||.||||||::.|.|:|||||||:|||||||||||||.:|||||||||:||||||||:|||||||
Human   149 LMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLA 213

  Fly   177 RPTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIME 241
            |.|::|||||||||||||||||||||||:|||||||||||||||:|.||||||||||.||.||:.
Human   214 RHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILR 278

  Fly   242 MLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEA 306
            ::|||.||.||||||||||:|||||..|...:|.|||..|||||:|||||||.||::|||||.:|
Human   279 LVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAAQA 343

  Fly   307 LSHPYLEKYAEPSVEQTSPPYDHSFEDMDLPVDKWKELIYKEVTNFKPPP 356
            |:|.|..:|.:|..|..:.|||.|||..||.:|:||.|.|.||.:|.|||
Human   344 LAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPP 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	223/306 (73%)
		S_TKc	25..312	CDD:214567	203/264 (77%)
MAPK14	XP_011512612.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	453	1.000	Domainoid score	I508
eggNOG	1	0.900	-	-		E1_KOG0660
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31777
Inparanoid	1	1.050	523	1.000	Inparanoid score	I1260
Isobase	1	0.950	-	0	Normalized mean entropy	S378
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	1	1.000	-	-		mtm8496
orthoMCL	1	0.900	-	-		OOG6_102675
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.780