Protein Alignment p38a and CDK3

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_001249.1
• Gene: CDK3 / 1018
• HGNCID: 1772
• Length: 305
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 118/314 - (37%)
• Similarity: 165/314 - (52%)
• Gaps: 40/314 - (12%)

  Fly    23 DIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGL 87
            |::|.::.:|.|.||.|.||..|.|...||:||:....:.........||:.|||.:.|.|::.|
Human     2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNIVRL 66

  Fly    88 LDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQ-------HLSDDHVQFLVYQILRGLKYI 145
            ||:.|         |.:::|||...:..||...:...       ||    ::..::|:|:|:.:.
Human    67 LDVVH---------NERKLYLVFEFLSQDLKKYMDSTPGSELPLHL----IKSYLFQLLQGVSFC 118

  Fly   146 HSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGY---VATRWYRAPEIMLNWMHYDQT 207
            ||..||||||||.|:.:||...:::.||||||.....:..|   |.|.|||||||:|....|...
Human   119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTA 183

  Fly   208 VDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKG- 271
            |||||:|||.||::||:.||||...|.||..|..|||||         ||.....:..||..||
Human   184 VDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTP---------SEDTWPGVTQLPDYKGS 239

  Fly   272 ------RSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPS 319
                  :..:.:..|..|...|||.::|:.|..:||||:.||:|||... .|||
Human   240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPS 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	118/314 (38%)
CDK3	NP_001249.1	STKc_CDK2_3	3..286	CDD:270844	113/304 (37%)