Protein Alignment p38a and CDK2

DIOPT Version :10

• Sequence 1: NP_477163.1
• Gene: p38a / 42866
• FlyBaseID: FBgn0015765
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: XP_011536034.1
• Gene: CDK2 / 1017
• HGNCID: 1771
• Length: 346
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 111/349 - (31%)
• Similarity: 161/349 - (46%)
• Gaps: 67/349 - (19%)

  Fly    25 YQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYRELRLLKHMDHENVIGLLD 89
            :|.::.:|.|.||.|.||..:.|...||:||:....::........||:.|||.::|.|::.|||
Human     4 FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLD 68

  Fly    90 IFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSD---DHVQFLVYQILRGLKYIHSAGVI 151
            :.|       .||  ::|||...:..||...:....|:.   ..::..::|:|:||.:.||..|:
Human    69 VIH-------TEN--KLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVL 124

  Fly   152 HRDLKPSNIAVNEDCELRILDFGLAR----PTENEMTGYVATRWYRAPEIMLNWMHYDQTVDIWS 212
            ||||||.|:.:|.:..:::.||||||    |... .|..|.|.|||||||:|...:|...|||||
Human   125 HRDLKPQNLLINTEGAIKLADFGLARAFGVPVRT-YTHEVVTLWYRAPEILLGCKYYSTAVDIWS 188

  Fly   213 VGCIMAEL------------------------------------------------ITRRTLFPG 229
            :|||.||:                                                :|||.||||
Human   189 LGCIFAEMHLVGTQHHARCCGEHRRNGRQSLCPLCSYLEVAASQGWGMTAVSTPYPVTRRALFPG 253

  Fly   230 TDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSLPPMKGRSFKNVFKNANPLAIDLLEKMLE 294
            ...|.||..|...||||.......::  |...|..|.|....:.|..|....:.....||.:||.
Human   254 DSEIDQLFRIFRTLGTPDEVVWPGVT--SMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLH 316

  Fly   295 LDAEKRITAEEALSHPYLEKYAEP 318
            .|..|||:|:.||:||:.:...:|
Human   317 YDPNKRISAKAALAHPFFQDVTKP 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_477163.1	STKc_p38	9..354	CDD:143356	111/349 (32%)
CDK2	XP_011536034.1	STKc_CDK2_3	3..334	CDD:270844	110/341 (32%)