DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment p38a and XB956263

DIOPT Version :9

Sequence 1:	NP_001163711.1	Gene:	p38a / 42866	FlyBaseID:	FBgn0015765	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	XP_002938433.1	Gene:	XB956263 / 100145045	XenbaseID:	XB-GENE-956264	Length:	359	Species:	Xenopus tropicalis

Alignment Length:	354	Identity:	201/354 - (56%)
Similarity:	259/354 - (73%)	Gaps:	4/354 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KKFYKLDINRTEWEIPDIYQDLQPVGSGAYGQVSKAVVRGTNMHVAIKKLARPFQSAVHAKRTYR 71
            |.||:.|||:|:|::|..|:||..|||||||.|..|..|.|...||||||.|||||.|||||.||
Frog     7 KGFYRQDINKTKWDVPVRYRDLAAVGSGAYGTVCSAQDRLTGERVAIKKLLRPFQSLVHAKRAYR 71

  Fly    72 ELRLLKHMDHENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRMQHLSDDHVQFLVY 136
            ||||||||.|||||.||::|.|   :.|:|.||..|||...:..||:.::|||.|:...:.:|:|
Frog    72 ELRLLKHMKHENVISLLNVFTP---DESMETFQTFYLVMPFIAVDLSRVMRMQRLNHSTIVYLLY 133

  Fly   137 QILRGLKYIHSAGVIHRDLKPSNIAVNEDCELRILDFGLARPTENEMTGYVATRWYRAPEIMLNW 201
            ||||||:|||:||::||||||||:.||||.||:|||||||||||.||||||.||||||||::|||
Frog   134 QILRGLQYIHAAGIVHRDLKPSNLGVNEDYELKILDFGLARPTEFEMTGYVVTRWYRAPEVILNW 198

  Fly   202 MHYDQTVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKISSESARSYIQSL 266
            |||:.||||||||||:||:||.:.||||.|:..:||.|:|:.|:|....:.|:.|..|:.|::.|
Frog   199 MHYNHTVDIWSVGCILAEMITGKVLFPGGDYFDELNKIIEVTGSPQPSLINKMESSHAQDYVKML 263

  Fly   267 PPMKGRSFKNVFKNANPLAIDLLEKMLELDAEKRITAEEALSHPYLEKYAEPSVEQTSPPYDHSF 331
            |..:.::||.:|...:.:..|||||||:||...|:.|.|||:|||||:|.:...:.|:..||.||
Frog   264 PKKQKKNFKELFPTMSAVETDLLEKMLDLDPGTRVNATEALAHPYLEEYNDSDPDPTADKYDDSF 328

  Fly   332 EDMDLPVDKWKELIYKEVTNFKP-PPSYA 359
            |.:||.|.:||.|.:.|:..|:| .||.|
Frog   329 ESLDLNVHEWKSLSHMEIMTFEPMKPSQA 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
p38a	NP_001163711.1	STKc_p38	9..354	CDD:143356	196/344 (57%)
p38a	NP_001163711.1	S_TKc	25..312	CDD:214567	170/286 (59%)
XB956263	XP_002938433.1	STKc_p38	9..351	CDD:143356	196/344 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324618at33208
OrthoFinder	1	1.000	-	-		FOG0000533
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X352
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020