Protein Alignment Kal1 and kal-1

DIOPT Version :9

• Sequence 1: NP_651220.3
• Gene: Kal1 / 42865
• FlyBaseID: FBgn0039155
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_493468.2
• Gene: kal-1 / 173282
• WormBaseID: WBGene00002181
• Length: 700
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 148/628 - (23%)
• Similarity: 234/628 - (37%)
• Gaps: 174/628 - (27%)

  Fly     6 VALLALLVLGQLFPSAVANGSSSYSSTSTSASNQ---LQRQKLAHWFRDSNDVKDKILEL----- 62
            :.||.|.:||.:.|..:         .||....|   |..|:|.:.......:|..|::|
 Worm     2 ILLLLLFILGSVSPDEL---------ISTRCQAQCLHLMDQRLQNNMELRKTLKHHIIQLCKEDA 57

  Fly    63 ---QCLAKCGSN-PTTKA---------GREQCLNKC-IQELLLGPRAGSCPKIGRQSRARLSCLD 113
               .|.|.|... ...||         .||.|.:.| ..:.:...:.|:||.:..||....|.|
 Worm    58 TCSACSAPCREQFDDIKACKKSCVASDDRETCEDSCHYLQRIYQEKPGACPSVSNQSNYECSAL- 121

  Fly   114 NCQYDHECPEVQKCCPSSCGPMCVEPLGVRNNTQLPPIPKILYFRRSRGHAVDLKIESSLLVYYF 178
             ||.|.||||.||||.|.|...|::|..  ::.:|.|||:.:..:       :.|.:.|::
 Worm   122 -CQMDGECPETQKCCSSGCSRQCLKPRS--SDIKLLPIPRNISVQ-------ERKRKRSII---- 172

  Fly   179 HVEVRSHIGRHFAARK-------LGPWQW--QKVEKTMEE----NIGHSKHTYIFFHMRPGRWYE 230
               :|...||...|::       |..|:|  ...|..|.|    .:.:..:..:...:.|||:||
 Worm   173 ---IRWATGRLSKAQQNENANLFLVQWRWGLHADESAMTEWQTVTVRNKPYAILKHLLSPGRFYE 234

  Fly   231 VRVAAVNAYGFRGYSEPSDPFPSTGNPKPPKSPND-----SKIIGKQFDGRYMTLKLVWCPSKSN 290
            .|.|||:..|..|:|.||.||..:...|.|..|.|     ||::.   .|.:..: :.|.|..|:
 Worm   235 FRTAAVSQEGSLGFSSPSKPFKISKEAKAPPPPKDLSLGASKVVA---SGLWNQM-VHWNPPPSD 295

  Fly   291 LPVEKYKITWSLYVNS---------AKASMITNSSYVK------DTHQF---------------- 324
            ||::.|:|:|:....|         .|.|.:..:::.|      |..:|
 Worm   296 LPIKNYQISWASSTKSEADAFEEQMRKKSTLEFAAHEKRSLQSDDDEEFIGIQERDRQSVVVPSH 360

  Fly   325 ----EIKELLPNSSYYIQVQAISYLGSRRLKSEQWSMLFNTTLQPL-------EPITPLQCSGNG 378
                ||..|.|||.|.:::.|........|..|: .::|..|...|       ||.|       |
 Worm   361 ATSSEITGLFPNSVYLVEIHASVDSSDGELHGEK-GVVFIRTADSLSAVPEDREPYT-------G 417

  Fly   379 NRRRHHHTS--------------SSMSSERATTSEPVALNEVSP-------TITNRTSAAATYEV 422
            .:.|..|.|              ||.:..|..:.:|..|...:|       |..|..:||.....
 Worm   418 PKARIAHGSEELKIEASLKDLKTSSHAPNRPNSPQPAHLEIQTPFFDTELQTQLNWLNAAHCTPA 482

  Fly   423 GFRLNRKFGMIVQ---ILGFQP--HKE-KVYELCPQETNCEQREFRAIRAKKDPLEFSKLKYNTT 481
                .|:|.:.|:   ...:||  |.: :.::|  :.|:|...             ...|.::..
 Worm   483 ----KRQFSVKVRKTLCREYQPNHHSDTRWHDL--RVTDCSAL-------------LKGLSFDCD 528

  Fly   482 YVLRIPRSSPNSVLDDSRNVFTFTTPKCENFRKRFPKLQIKCS 524
            |.:.:..:.....:.|.    .|:|..|:......|   |.||
 Worm   529 YKVEVTDTLTGDFVVDG----VFSTDTCDQTSSLTP---IDCS 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kal1	NP_651220.3	WAP	96..139	CDD:278522	21/42 (50%)
		fn3	<177..245	CDD:278470	21/80 (26%)
		fn3	279..343	CDD:278470	22/98 (22%)
kal-1	NP_493468.2	WAP	<102..146	CDD:238120	21/45 (47%)
		fn3	157..249	CDD:278470	24/105 (23%)
		FN3	570..654	CDD:238020

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167642
Domainoid	1	1.000	61	1.000	Domainoid score	I6971
eggNOG	1	0.900	-	-		E1_KOG4802
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I3515
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415772at33208
OrthoFinder	1	1.000	-	-		FOG0007219
OrthoInspector	1	1.000	-	-		oto20152
orthoMCL	1	0.900	-	-		OOG6_107197
Panther	1	1.100	-	-	LDO	PTHR14131
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3210
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.790