Protein Alignment Sec10 and Exoc5

DIOPT Version :9

• Sequence 1: NP_651218.1
• Gene: Sec10 / 42863
• FlyBaseID: FBgn0266673
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_071540.1
• Gene: Exoc5 / 60627
• RGDID: 708408
• Length: 708
• Species: Rattus norvegicus
• Alignment Length: 697
• Identity: 298/697 - (42%)
• Similarity: 454/697 - (65%)
• Gaps: 10/697 - (1%)

  Fly     8 EFEQEPFEVGEFIERLTWRT--NNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEES 70
            |..:|||...|:||||.|||  .......|.|.|..|.:.|:..|::|:|:.|:.|.|.|:||:.
  Rat     6 ELFEEPFVADEYIERLVWRTPGGGSRGGPEAFDPKRLLEEFVNHIQELQIMDERIQRKVEKLEQQ 70

  Fly    71 LRQEKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLLN 135
            .::|.:..|||:.:||:.:|.|...|.:|||.|:.||.|:.|||:|||.|||||.|:||||||:.
  Rat    71 CQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMK 135

  Fly   136 FMSEFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLIE 200
            :.:|||..  .:.:|:|.:..::.|||||||||:.|:|:||...|:|.|.||..||.::|.:||:
  Rat   136 YFNEFLDG--ELKSDVFTNPEKIKEAADVIQKLHLIAQELPFDRFSEVKSKIASKYHDLECQLIQ 198

  Fly   201 EFATAQKSEDIERMKTLAQILSQFKGYTQCVDAYIEQSQMQPYSGKDIFIGIVPLCKHHYEIIQK 265
            ||.:||:..::.||:.:|.:|..||||:.|:|.||:|.|...|...|||.....||:...:.:..
  Rat   199 EFTSAQRRGEVSRMREVAAVLLHFKGYSHCIDVYIKQCQEGAYLRNDIFEDAAILCQRVNKQVGD 263

  Fly   266 VFANPQQVMSKFILNIYQLKLHQYAMTKLED--KKDEEKYLRTLYELYSRTLKLSTDL-QIYMST 327
            :|:||:.|::|.|.|::::||..:...:||:  |.|.|:||::||:||:||..||:.| :..:.|
  Rat   264 IFSNPEAVLAKLIQNVFEVKLQSFVKDQLEECRKSDAEQYLKSLYDLYTRTTSLSSKLMEFNLGT 328

  Fly   328 IDDDLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEVLIAT 392
            .....|.||.:.||:.:|..|.|:|...|.::.:..|:::|.||.|||.:...|..::::..|..
  Rat   329 DKQTFLSKLIKSIFVSYLENYIEVEIGYLKSRSAMILQRYYDSKNHQKRSIGTGGIQDLKERIRQ 393

  Fly   393 RANINIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFLMHEH 457
            |.|:.:....|..||||||:|:.:|:|||.|.:.:||..||:.::||.||.::..||:.||..||
  Rat   394 RTNLPLGPSIDTHGETFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEH 458

  Fly   458 VDYALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYVFKKR 522
            :|||||.||..:|.::.| ...|||.||||:.|.|.||.||..:..::|.:|::||.|:.:.||:
  Rat   459 IDYALETGLAGIPSSDSR-NANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLSECLQKKK 522

  Fly   523 ILMEQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPETDVDTI--SSAACLQVVQNLQPVI 585
            .::||:|.|||.|:||:::.:||.:|..|..||||||:|||.:.:.:  .:.||::|...::..:
  Rat   523 EIIEQMEMKLDTGIDRTLNCMIGQMKHILAAEQKKTDFKPEDENNVLIQYTNACVKVCAYVRKQV 587

  Fly   586 VQIKKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPLVTQ 650
            .:||..:||:|:..||.|.|.|.||:.|:|||...::..|.|.|||||.|||||.::...|:|..
  Rat   588 EKIKNSMDGKNVDTVLMELGVRFHRLTYEHLQQYSYSCMGGMLAICDVAEYRKCAKDFKIPMVLH 652

  Fly   651 LFDILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFR 697
            |||.||||||||:|.|.||::||:|:.|..|||:::..|:|||.|:|
  Rat   653 LFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYR 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec10	NP_651218.1	RILP-like	46..>103	CDD:304877	22/56 (39%)
		Sec10	89..705	CDD:284746	266/614 (43%)
Exoc5	NP_071540.1	Sec10	89..707	CDD:399988	266/614 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346154
Domainoid	1	1.000	520	1.000	Domainoid score	I292
eggNOG	1	0.900	-	-		E1_KOG3745
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38195
Inparanoid	1	1.050	578	1.000	Inparanoid score	I1000
OMA	1	1.010	-	-		QHG54308
OrthoDB	1	1.010	-	-		D225235at2759
OrthoFinder	1	1.000	-	-		FOG0004379
OrthoInspector	1	1.000	-	-		oto96106
orthoMCL	1	0.900	-	-		OOG6_102983
Panther	1	1.100	-	-	LDO	PTHR12100
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5499
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770