Protein Alignment Sec10 and exoc5

DIOPT Version :10

• Sequence 1: NP_651218.1
• Gene: Sec10 / 42863
• FlyBaseID: FBgn0266673
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001107268.1
• Gene: exoc5 / 559010
• ZFINID: ZDB-GENE-080204-126
• Length: 708
• Species: Danio rerio
• Alignment Length: 694
• Identity: 288/694 - (41%)
• Similarity: 445/694 - (64%)
• Gaps: 10/694 - (1%)

  Fly    11 QEPFEVGEFIERLTWRT--NNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEESLRQ 73
            :|||:..|:||||.|||  ......:|.|.|..|.:.|:..|::||:|.|:.|.|.|:||:...:
Zfish     9 EEPFDADEYIERLAWRTPGGGSKGGAEAFDPKKLLEEFVNHIEELKLLDERIQRKVEKLEQQCHR 73

  Fly    74 EKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLLNFMS 138
            |.:..|.|:..||..:|.|...|.:|||.|:.||.|:.|||:|||.|||||.|:||||:|:.:.:
Zfish    74 EAKEFAHKVQDLQRSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQRLMTYFN 138

  Fly   139 EFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLIEEFA 203
            |||..  .:.:|:|.:..::.||||:||||:.|:|:||...|::.|.||..||.::||:||:||.
Zfish   139 EFLDG--ELRSDVFNNPEKIKEAADIIQKLHLIAQELPFDRFSDVKAKIASKYHDLERQLIQEFT 201

  Fly   204 TAQKSEDIERMKTLAQILSQFKGYTQCVDAYIEQSQMQPYSGKDIFIGIVPLCKHHYEIIQKVFA 268
            .||:..:|.||:.:|.:|..||||..|||.||:|.|...|...|:|..|..||:...:.:.:||.
Zfish   202 AAQRRGEIGRMREVAAVLLHFKGYAHCVDVYIKQCQEGAYMRNDVFEDIAILCQRVNKQVGEVFC 266

  Fly   269 NPQQVMSKFILNIYQLKLHQYAMTKLEDKK--DEEKYLRTLYELYSRTLKLSTDLQIY-MSTIDD 330
            :|:.||:|.|.:|::.|:..:...:|::.:  |.|:||:.||:||:||..|:..|..| :.:...
Zfish   267 SPETVMAKLIQSIFENKIQAHVKERLDETRNSDVEQYLKNLYDLYTRTTALAAKLTDYNLGSDKH 331

  Fly   331 DLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEVLIATRAN 395
            ..|.||.:.||..:|..|.:||.:.|..:....|:::|.||.|||.....|..:.::..|..|.|
Zfish   332 TFLSKLIKNIFSCYLESYIDMERQYLQNRSGMILQRYYDSKNHQKRPVGTGSIQELKERIRQRTN 396

  Fly   396 INIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFLMHEHVDY 460
            :.:....|..|||.||:|:.:|:|||.:.:.:||..||:..:||.||..:..||:.:|..:|:||
Zfish   397 LPLGPSIDTHGETLLSQEVVVNLLQETRHAFERCNKLSDPADLPKNAFSIFLILVEYLCVDHIDY 461

  Fly   461 ALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYVFKKRILM 525
            |||:||.|:|.|:.: ...|||.||||:.|.|.||.||..:..::|.:|::||.::.:.||:.::
Zfish   462 ALEIGLSAIPSADAK-NANLYFLDVVQQANTIFHLFDKQFNDHLMPLISSSPKLTECLHKKKEVI 525

  Fly   526 EQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPETDVDTI--SSAACLQVVQNLQPVIVQI 588
            ||:|.|||.|:||:::.:||.:|..|..||||||:|||.:.:.:  .:.||.:|...:...:.::
Zfish   526 EQMEVKLDTGIDRTLNCMIGQMKYILTTEQKKTDFKPEDENNVMIQYTTACSKVCAYVGKQVERV 590

  Fly   589 KKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPLVTQLFD 653
            ::.:||:|:..||||.|.|.||:|::|||...:::.|.|.|||||.|||:..::...|||.||||
Zfish   591 RRSMDGKNVDTVLTELGVRFHRLIHEHLQQFSYSSMGGMLAICDVAEYRRSAKDFRVPLVLQLFD 655

  Fly   654 ILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFR 697
            .||||||||:|.|.||::||:|:.|..||::::..|:|||.|:|
Zfish   656 TLHALCNLLVVAPDNLKQVCSGEQLTNLDRNLLHAFVQLRVDYR 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec10	NP_651218.1	Sec10	89..705	CDD:399988	257/614 (42%)
exoc5	NP_001107268.1	Sec10	89..707	CDD:399988	257/614 (42%)