Protein Alignment Sec10 and exoc5

DIOPT Version :10

• Sequence 1: NP_651218.1
• Gene: Sec10 / 42863
• FlyBaseID: FBgn0266673
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001017342.1
• Gene: exoc5 / 550096
• XenbaseID: XB-GENE-971692
• Length: 708
• Species: Xenopus tropicalis
• Alignment Length: 697
• Identity: 299/697 - (42%)
• Similarity: 454/697 - (65%)
• Gaps: 10/697 - (1%)

  Fly     8 EFEQEPFEVGEFIERLTWRT--NNELQNSEDFHPVALHDTFIQTIKDLKILQEKQQSKCERLEES 70
            |..:|||...|:||||.|||  .......|.|.|..|.:.|:..|.:||::.|:.|.|.|:||:.
 Frog     6 ELFEEPFVADEYIERLAWRTPGGGSRGGVESFDPKRLLEQFVNHIDELKLMDERIQRKVEKLEQQ 70

  Fly    71 LRQEKESHAKKIAKLQERHQTAIDVFGQLDEKINSVAGKIMHLGEQLENVNTPRSRSVEAQKLLN 135
            .::|.:..|||:.:||:.:|.|...|.:|||.|:.||.|:.|||:|||.|||||.|:||||||:.
 Frog    71 CQKEAKEFAKKVQELQKSNQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMT 135

  Fly   136 FMSEFLAAGPVIVNDIFADAARLSEAADVIQKLYAISQDLPPGNFAESKRKIEKKYDEVERRLIE 200
            :.:|||..  .:.:|:|.:..::.||||:||||:.|:|:||...|||.|.||..||.::|.:||:
 Frog   136 YFNEFLDG--ELRSDVFNNPEKIKEAADIIQKLHLIAQELPFDRFAEVKSKIASKYHDLEHQLIQ 198

  Fly   201 EFATAQKSEDIERMKTLAQILSQFKGYTQCVDAYIEQSQMQPYSGKDIFIGIVPLCKHHYEIIQK 265
            ||.:||:..:|.||:.:|.:|..||||:.|||.||.|.|...|...|||.....||:.....:..
 Frog   199 EFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYINQCQEGAYLKYDIFENSAVLCQRVNREVGD 263

  Fly   266 VFANPQQVMSKFILNIYQLKLHQYAMTKLED--KKDEEKYLRTLYELYSRTLKLSTDL-QIYMST 327
            :|:||:.|::|.|.||:::|:......:|::  |.|.|:||::||:||:||..||:.| :..:.|
 Frog   264 IFSNPEIVLAKLIQNIFEVKIQSCVKEQLDECRKSDAEQYLKSLYDLYTRTTGLSSKLMEFNLGT 328

  Fly   328 IDDDLLQKLTQQIFIKHLAGYAEMETKCLTAKCSTELEKFYASKKHQKTATTKGFRRNMEVLIAT 392
            .....|.||.:.|||.:|..|.::||..|.::.|..|:::|.||.|||.....|..::::..|..
 Frog   329 DKQTFLSKLIKSIFISYLENYIDVETAYLRSRSSVILQRYYDSKNHQKRPIGGGGIQDLKERIRQ 393

  Fly   393 RANINIAAIEDYGGETFLSEELAINMLQEAKASLKRCRLLSNETELPGNAIKLNDILLRFLMHEH 457
            |.|:.:....|..||||||:|:.:|:|||.|.:.:||..||:.::||.||.::..||:.:|..||
 Frog   394 RTNLPLGPSIDTHGETFLSQEVVVNLLQETKHAFERCHKLSDPSDLPKNAFRIFSILVDYLCIEH 458

  Fly   458 VDYALELGLQAVPLAEGRVFPQLYFFDVVQKTNIIVHLLDKLCHTSVIPCVSNTPKYSDYVFKKR 522
            :|||||:||.|:|..:.: ...|||||||.:.|.|.||.||..:..::|.:|::||.::.:.||:
 Frog   459 IDYALEIGLVAIPSPDSK-NANLYFFDVVHQANTIFHLFDKQFNDHLMPLISSSPKLTECLQKKK 522

  Fly   523 ILMEQIETKLDQGLDRSISAVIGWVKVYLQYEQKKTDYKPETDVDTI--SSAACLQVVQNLQPVI 585
            .::||:|.|||.|:||:|:.::|.:|..|..||||||:|||.:.:.:  .:.||::|...::..:
 Frog   523 EIIEQMEVKLDTGIDRTINCMVGQMKQILAAEQKKTDFKPEDENNVLIQYTTACVKVCLYVRKQV 587

  Fly   586 VQIKKCVDGENLQNVLTEFGTRLHRVIYDHLQTMQFNTAGAMCAICDVNEYRKCIRELDSPLVTQ 650
            .:|:..:||:|:..||.|.|.|.||:||:|||...:::.|.|.|||||.|||:|.::...|||.|
 Frog   588 EKIRNSMDGKNVDTVLMELGVRFHRLIYEHLQQFSYSSMGGMLAICDVAEYRRCAKDFKIPLVLQ 652

  Fly   651 LFDILHALCNLLLVKPQNLQEVCTGDTLNYLDKSVVRQFIQLRTDFR 697
            |||.||:|||||:|.|.||::||:|:.|..|||:::..|:|||.|:|
 Frog   653 LFDTLHSLCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYR 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec10	NP_651218.1	Sec10	89..705	CDD:399988	267/614 (43%)
exoc5	NP_001017342.1	Sec10	89..707	CDD:399988	267/614 (43%)